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Journal of Nuclear Medicine

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Table of Contents

October 1, 2018; Volume 59,Issue 10

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 6A;

Issues and Controversies

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    Nuclear Medicine Procedures Do Not Pose Cancer Risks in Women—Unappreciated or Otherwise
    Jeffry A. Siegel, Bennett Greenspan, Edward B. Silberstein, Bill Sacks, Carol S. Marcus and Michael G. Stabin
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1489-1490; DOI: https://doi.org/10.2967/jnumed.118.218842
  • REPLY

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      Nuclear Medicine Procedures Do Not Pose Cancer Risks in Women—Unappreciated or Otherwise
      Anat Biegon, Dinko Franceschi and Mark Schweitzer
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1491; DOI: https://doi.org/10.2967/jnumed.118.218834

Hot Topics

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    Assessment of the Right-to-Try Law: The Pros and the Cons
    Brandon Brown, Camerin Ortiz and Karine Dubé
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1492-1493; DOI: https://doi.org/10.2967/jnumed.118.216945

The State of the Art

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    The Relevance of Dosimetry in Precision Medicine
    Michael Lassmann and Uta Eberlein
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1494-1499; DOI: https://doi.org/10.2967/jnumed.117.206649

Continuing Education

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    An Overview of PET Radiochemistry, Part 2: Radiometals
    Marie Brandt, Jens Cardinale, Margaret L. Aulsebrook, Gilles Gasser and Thomas L. Mindt
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1500-1506; DOI: https://doi.org/10.2967/jnumed.117.190801

Editorial

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    Modern Radiopharmaceutical Dosimetry Should Include Robust Biodistribution Reporting
    Adam L. Kesner and Lisa Bodei
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1507-1509; DOI: https://doi.org/10.2967/jnumed.118.208603

Oncology

  • Clinical

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      Role of Diagnostic 131I SPECT/CT in Long-Term Follow-up of Patients with Papillary Thyroid Microcarcinoma
      Angela Spanu, Susanna Nuvoli, Ilaria Gelo, Luciana Mele, Bastiana Piras and Giuseppe Madeddu
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1510-1515; DOI: https://doi.org/10.2967/jnumed.117.204636
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      Reproducibility and Repeatability of Semiquantitative 18F-Fluorodihydrotestosterone Uptake Metrics in Castration-Resistant Prostate Cancer Metastases: A Prospective Multicenter Study
      Hebert Alberto Vargas, Gem M. Kramer, Andrew M. Scott, Andrew Weickhardt, Andreas A. Meier, Nicole Parada, Bradley J. Beattie, John L. Humm, Kevin D. Staton, Pat B. Zanzonico, Serge K. Lyashchenko, Jason S. Lewis, Maqsood Yaqub, Ramon E. Sosa, Alfons J. van den Eertwegh, Ian D. Davis, Uwe Ackermann, Kunthi Pathmaraj, Robert C. Schuit, Albert D. Windhorst, Sue Chua, Wolfgang A. Weber, Steven M. Larson, Howard I. Scher, Adriaan A. Lammertsma, Otto S. Hoekstra and Michael J. Morris
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1516-1523; DOI: https://doi.org/10.2967/jnumed.117.206490
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      18F-FDG PET Response of Skeletal (Bone Marrow and Bone) Involvement After Induction Chemotherapy in Pediatric Hodgkin Lymphoma: Are Specific Response Criteria Required?
      Thomas W. Georgi, Regine Kluge, Lars Kurch, Lidia Chavdarova, Dirk Hasenclever, Dietrich Stoevesandt, Tanja Pelz, Judith Landman-Parker, W. Hamish Wallace, Jonas Karlen, Ana Fernández-Teijeiro, Michaela Cepelova, Alexander Fosså, Walentyna Balwierz, Andishe Attarbaschi, Roland A. Ammann, Jane Pears, Andrea Hraskova, Anne Uyttebroeck, Auke Beishuizen, Karin Dieckmann, Thierry Leblanc, Stephen Daw, Julia Baumann, Dieter Körholz, Osama Sabri and Christine Mauz-Körholz
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1524-1530; DOI: https://doi.org/10.2967/jnumed.117.205633
  • Basic

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      PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with 89Zr-Oxine
      Michael R. Weist, Renate Starr, Brenda Aguilar, Junie Chea, Joshua K. Miles, Erasmus Poku, Ethan Gerdts, Xin Yang, Saul J. Priceman, Stephen J. Forman, David Colcher, Christine E. Brown and John E. Shively
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1531-1537; DOI: https://doi.org/10.2967/jnumed.117.206714
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      Specific 18F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone–Binding Globulin
      Benjamin M. Larimer, Frank Dubois, Emily Bloch, Sarah Nesti, Michael Placzek, Giorgia Zadra, Jacob M. Hooker, Massimo Loda and Umar Mahmood
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1538-1543; DOI: https://doi.org/10.2967/jnumed.118.208785
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      Using Radiolabeled 3′-Deoxy-3′-18F-Fluorothymidine with PET to Monitor the Effect of Dexamethasone on Non–Small Cell Lung Cancer
      Christopher I. McHugh, Monica R. Thipparthi, Jawana M. Lawhorn-Crews, Lisa Polin, Shirish Gadgeel, Janice Akoury, Thomas J. Mangner, Kirk A. Douglas, Jing Li, Manohar Ratnam and Anthony F. Shields
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1544-1550; DOI: https://doi.org/10.2967/jnumed.117.207258
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      Imaging Melphalan Therapy Response in Preclinical Extramedullary Multiple Myeloma with 18F-FDOPA and 18F-FDG PET
      Deep K. Hathi, Elizabeth N. DeLassus, Samuel Achilefu, Jonathan McConathy and Monica Shokeen
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1551-1557; DOI: https://doi.org/10.2967/jnumed.118.208744
    • Open Access
      Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using 18F-ICMT-11 and 18F-FLT PET
      Kathrin Heinzmann, Quang-Dé Nguyen, Davina Honess, Donna-Michelle Smith, Stephen Stribbling, Diana Brickute, Chris Barnes, John Griffiths and Eric Aboagye
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1558-1565; DOI: https://doi.org/10.2967/jnumed.118.209304

Theranostics

  • Clinical

    • FEATURED CLINICAL INVESTIGATION ARTICLE

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        Quality of Life in Patients with Metastatic Gastroenteropancreatic Neuroendocrine Tumors Receiving Peptide Receptor Radionuclide Therapy: Information from a Monitoring Program in Clinical Routine
        Caroline Martini, Sabine Buxbaum, Margarida Rodrigues, Bernhard Nilica, Lorenza Scarpa, Bernhard Holzner, Irene Virgolini and Eva-Maria Gamper
        Journal of Nuclear Medicine October 1, 2018, 59 (10) 1566-1573; DOI: https://doi.org/10.2967/jnumed.117.204834

Cardiology

  • Clinical

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      Simplified Quantification and Acquisition Protocol for 123I-MIBG Dynamic SPECT
      Jing Wu, Jean-Dominique Gallezot, Yihuan Lu, Qing Ye, Hui Liu, Denise A. Esserman, Tassos C. Kyriakides, Stephanie L. Thorn, Taraneh Hashemi Zonouz, Yi-Hwa Liu, Rachel J. Lampert, Albert J. Sinusas, Richard E. Carson and Chi Liu
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1574-1580; DOI: https://doi.org/10.2967/jnumed.117.202143

Neurology

  • Clinical

    • INVITED PERSPECTIVE

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        Optimizing Longitudinal Amyloid-β PET Measurement: The Challenges of Intensity Normalization
        Susan M. Landau
        Journal of Nuclear Medicine October 1, 2018, 59 (10) 1581-1582; DOI: https://doi.org/10.2967/jnumed.118.212662
    • You have access
      White Matter Reference Region in PET Studies of 11C-Pittsburgh Compound B Uptake: Effects of Age and Amyloid-β Deposition
      Val J. Lowe, Emily S. Lundt, Matthew L. Senjem, Christopher G. Schwarz, Hoon-Ki Min, Scott A. Przybelski, Kejal Kantarci, David Knopman, Ronald C. Petersen and Clifford R. Jack
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1583-1589; DOI: https://doi.org/10.2967/jnumed.117.204271
    • Open Access
      Age-Specific 18F-FDG Image Processing Pipelines and Analysis Are Essential for Individual Mapping of Seizure Foci in Pediatric Patients with Intractable Epilepsy
      Bianca De Blasi, Anna Barnes, Ilaria Boscolo Galazzo, Chia-ho Hua, Barry Shulkin, Matthias Koepp and Martin Tisdall
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1590-1596; DOI: https://doi.org/10.2967/jnumed.117.203950
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      Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 Binding Site in Human Brain
      Robin J. Tyacke, Jim F.M. Myers, Ashwin Venkataraman, Inge Mick, Samuel Turton, Jan Passchier, Stephen M. Husbands, Eugenii A. Rabiner, Roger N. Gunn, Philip S. Murphy, Christine A. Parker and David J. Nutt
      Journal of Nuclear Medicine October 1, 2018, 59 (10) 1597-1602; DOI: https://doi.org/10.2967/jnumed.118.208009
  • Translational

    • FEATURED ARTICLE OF THE MONTH

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        18F-XTRA PET for Enhanced Imaging of the Extrathalamic α4β2 Nicotinic Acetylcholine Receptor
        Jennifer M. Coughlin, Stephanie Slania, Yong Du, Hailey B. Rosenthal, Wojciech G. Lesniak, Il Minn, Gwenn S. Smith, Robert F. Dannals, Hiroto Kuwabara, Dean F. Wong, Yuchuan Wang, Andrew G. Horti and Martin G. Pomper
        Journal of Nuclear Medicine October 1, 2018, 59 (10) 1603-1608; DOI: https://doi.org/10.2967/jnumed.117.205492
    • Basic

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        P-Glycoprotein (ABCB1) Inhibits the Influx and Increases the Efflux of 11C-Metoclopramide Across the Blood–Brain Barrier: A PET Study on Nonhuman Primates
        Sylvain Auvity, Fabien Caillé, Solène Marie, Catriona Wimberley, Martin Bauer, Oliver Langer, Irène Buvat, Sébastien Goutal and Nicolas Tournier
        Journal of Nuclear Medicine October 1, 2018, 59 (10) 1609-1615; DOI: https://doi.org/10.2967/jnumed.118.210104

Infection/Inflammation

  • Basic

    • FEATURED BASIC SCIENCE ARTICLE

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        18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis
        Jessica R. Salas, Bao Ying Chen, Alicia Wong, Donghui Cheng, John S. Van Arnam, Owen N. Witte and Peter M. Clark
        Journal of Nuclear Medicine October 1, 2018, 59 (10) 1616-1623; DOI: https://doi.org/10.2967/jnumed.118.210328

Physics and Instrumentation

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    Improving the Accuracy of Simultaneously Reconstructed Activity and Attenuation Maps Using Deep Learning
    Donghwi Hwang, Kyeong Yun Kim, Seung Kwan Kang, Seongho Seo, Jin Chul Paeng, Dong Soo Lee and Jae Sung Lee
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1624-1629; DOI: https://doi.org/10.2967/jnumed.117.202317
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    Joint Reconstruction of Activity and Attenuation in Time-of-Flight PET: A Quantitative Analysis
    Ahmadreza Rezaei, Christophe M. Deroose, Thomas Vahle, Fernando Boada and Johan Nuyts
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1630-1635; DOI: https://doi.org/10.2967/jnumed.117.204156

Special Contribution

  • Open Access
    The SNMMI and EANM Procedural Guidelines for Diuresis Renography in Infants and Children
    Massoud Majd, Zvi Bar-Sever, Ana Isabel Santos and Diego De Palma
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1636-1640; DOI: https://doi.org/10.2967/jnumed.118.215921

Book Reviews

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    Imaging in Stem Cell Transplant and Cell-Based Therapy
    June-Key Chung and Seunggyun Ha
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1641; DOI: https://doi.org/10.2967/jnumed.118.219154

Letters to the Editor

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    Neurometabolic Resting-State Networks Derived from Seed-Based Functional Connectivity Analysis
    Nicola Trotta, Kristof Baete, Koen Van Laere, Serge Goldman, Xavier De Tiège and Vincent Wens
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1642-1643; DOI: https://doi.org/10.2967/jnumed.118.212878
  • You have access
    Reply: Neurometabolic Resting-State Networks Derived from Seed-Based Functional Connectivity Analysis
    Isabelle Ripp, Alexandre Savio and Igor Yakushev
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1643; DOI: https://doi.org/10.2967/jnumed.118.216150
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    Semiquantification Limitations: FMTVDM©℗ Demonstrates Quantified Tumor Response to Treatment with Both Regional Blood Flow and Metabolic Changes
    Richard M. Fleming, Matthew R. Fleming, Andrew McKusick and Tapan K. Chaudhuri
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1643-1644; DOI: https://doi.org/10.2967/jnumed.118.217018
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    Reply: Semiquantification Limitations: FMTVDM©℗ Demonstrates Quantified Tumor Response to Treatment with Both Regional Blood Flow and Metabolic Changes
    Olivier Humbert, François Brunotte and Alexandre Cochet
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 1644; DOI: https://doi.org/10.2967/jnumed.118.218313

SNMMI Newsline

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    2018 SNMMI Highlights Lecture: General Nuclear Medicine
    Heather A. Jacene
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 7N-13N;
  • You have access
    Newsbriefs
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 13N;
  • You have access
    SNMMI Recognizes Outstanding Contributions at 2018 Annual Meeting
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 14N-16N;
  • You have access
    FDA Approves AZEDRA Specified Use in Pheochromocytomas/Paragangliomas
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 17N;
  • You have access
    SNMMI Leadership Update: SNMMI Mid-Winter Meeting in Palm Springs: Focus on Cardiovascular Imaging
    Virginia Pappas
    Journal of Nuclear Medicine October 1, 2018, 59 (10) 18N;
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In this issue

Journal of Nuclear Medicine: 59 (10)
Journal of Nuclear Medicine
Vol. 59, Issue 10
October 1, 2018
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • 18F-XTRA PET for Enhanced Imaging of the Extrathalamic α4β2 Nicotinic Acetylcholine Receptor
  • Quality of Life in Patients with Metastatic Gastroenteropancreatic Neuroendocrine Tumors Receiving Peptide Receptor Radionuclide Therapy: Information from a Monitoring Program in Clinical Routine
  • 18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis
  • The Relevance of Dosimetry in Precision Medicine
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  • Theranostics
    • Clinical
      • FEATURED CLINICAL INVESTIGATION ARTICLE
  • Cardiology
    • Clinical
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    • Clinical
      • INVITED PERSPECTIVE
    • Translational
      • FEATURED ARTICLE OF THE MONTH
      • Basic
  • Infection/Inflammation
    • Basic
      • FEATURED BASIC SCIENCE ARTICLE
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  • MIRD Pamphlet No. 28, Part 1: MIRDcalc—A Software Tool for Medical Internal Radiation Dosimetry
  • Absorbed Dose–Response Relationship in Patients with Gastroenteropancreatic Neuroendocrine Tumors Treated with [177Lu]Lu-DOTATATE: One Step Closer to Personalized Medicine
  • Prediction of 177Lu-DOTATATE PRRT Outcome Using Multimodality Imaging in Patients with Gastroenteropancreatic Neuroendocrine Tumors: Results from a Prospective Phase II LUMEN Study
  • Renal and Multiorgan Safety of 177Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer in the VISION Dosimetry Substudy
  • High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections
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