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Research ArticleNeurology

Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts

Daniel S. Albrecht, Marc D. Normandin, Sergey Shcherbinin, Dustin W. Wooten, Adam J. Schwarz, Nicole R. Zürcher, Vanessa N. Barth, Nicolas J. Guehl, Oluwaseun Akeju, Nazem Atassi, Mattia Veronese, Federico Turkheimer, Jacob M. Hooker and Marco L. Loggia
Journal of Nuclear Medicine January 2018, 59 (1) 107-114; DOI: https://doi.org/10.2967/jnumed.116.178335
Daniel S. Albrecht
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
2Gordon Center for Medical Imaging, NMMI, Radiology Department, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts
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Marc D. Normandin
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
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Sergey Shcherbinin
3Eli Lilly and Company, Indianapolis, Indiana
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Dustin W. Wooten
2Gordon Center for Medical Imaging, NMMI, Radiology Department, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts
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Adam J. Schwarz
3Eli Lilly and Company, Indianapolis, Indiana
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Nicole R. Zürcher
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
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Vanessa N. Barth
3Eli Lilly and Company, Indianapolis, Indiana
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Nicolas J. Guehl
2Gordon Center for Medical Imaging, NMMI, Radiology Department, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts
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Oluwaseun Akeju
4Department of Anesthesiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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Nazem Atassi
5Neurological Clinical Research Institute, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; and
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Mattia Veronese
6Department of Neuroimaging, Institute of Psychiatry, King's College London, London, United Kingdom
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Federico Turkheimer
6Department of Neuroimaging, Institute of Psychiatry, King's College London, London, United Kingdom
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Jacob M. Hooker
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
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Marco L. Loggia
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
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Article Information

vol. 59 no. 1 107-114
DOI 
https://doi.org/10.2967/jnumed.116.178335
PubMed 
28818984

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication August 12, 2016
  • Accepted for publication July 17, 2017
  • Published online January 2, 2018.

Article Versions

  • previous version (August 17, 2017 - 04:35).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2018 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Daniel S. Albrecht1,2,
  2. Marc D. Normandin1,
  3. Sergey Shcherbinin3,
  4. Dustin W. Wooten2,
  5. Adam J. Schwarz3,
  6. Nicole R. Zürcher1,
  7. Vanessa N. Barth3,
  8. Nicolas J. Guehl2,
  9. Oluwaseun Akeju4,
  10. Nazem Atassi5,
  11. Mattia Veronese6,
  12. Federico Turkheimer6,
  13. Jacob M. Hooker1 and
  14. Marco L. Loggia1
  1. 1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
  2. 2Gordon Center for Medical Imaging, NMMI, Radiology Department, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts
  3. 3Eli Lilly and Company, Indianapolis, Indiana
  4. 4Department of Anesthesiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  5. 5Neurological Clinical Research Institute, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; and
  6. 6Department of Neuroimaging, Institute of Psychiatry, King's College London, London, United Kingdom
  1. For correspondence or reprints contact: Marco L. Loggia, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 Thirteenth St., Rm. 2301, Charlestown, MA 02129. E-mail: marco{at}nmr.mgh.harvard.edu
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Journal of Nuclear Medicine: 59 (1)
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January 1, 2018
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Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts
Daniel S. Albrecht, Marc D. Normandin, Sergey Shcherbinin, Dustin W. Wooten, Adam J. Schwarz, Nicole R. Zürcher, Vanessa N. Barth, Nicolas J. Guehl, Oluwaseun Akeju, Nazem Atassi, Mattia Veronese, Federico Turkheimer, Jacob M. Hooker, Marco L. Loggia
Journal of Nuclear Medicine Jan 2018, 59 (1) 107-114; DOI: 10.2967/jnumed.116.178335

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Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts
Daniel S. Albrecht, Marc D. Normandin, Sergey Shcherbinin, Dustin W. Wooten, Adam J. Schwarz, Nicole R. Zürcher, Vanessa N. Barth, Nicolas J. Guehl, Oluwaseun Akeju, Nazem Atassi, Mattia Veronese, Federico Turkheimer, Jacob M. Hooker, Marco L. Loggia
Journal of Nuclear Medicine Jan 2018, 59 (1) 107-114; DOI: 10.2967/jnumed.116.178335
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