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Journal of Nuclear Medicine

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Research ArticleHot Topics

Is Tau Imaging More Than Just Upside-Down 18F-FDG Imaging?

Thilo van Eimeren, Gérard N. Bischof and Alexander Drzezga
Journal of Nuclear Medicine September 2017, 58 (9) 1357-1359; DOI: https://doi.org/10.2967/jnumed.117.190082
Thilo van Eimeren
1Multimodal Neuroimaging Group, Department of Nuclear Medicine, University of Cologne, Cologne, Germany; and
2German Research Center for Neurodegenerative Diseases (DZNE), Bonn/Cologne, Germany
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Gérard N. Bischof
1Multimodal Neuroimaging Group, Department of Nuclear Medicine, University of Cologne, Cologne, Germany; and
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Alexander Drzezga
1Multimodal Neuroimaging Group, Department of Nuclear Medicine, University of Cologne, Cologne, Germany; and
2German Research Center for Neurodegenerative Diseases (DZNE), Bonn/Cologne, Germany
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    FIGURE 1.

    Spatial correspondence of mean 18F-FDG deviation and mean tau deviation but not amyloid deviation in patients with AD. Deviation images were projected on lateral surface of left and right hemispheres using FreeSurfer. (Reprinted with permission of (13).)

  • FIGURE 2.
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    FIGURE 2.

    Clearly abnormal tau PET findings but barely abnormal 18F-FDG PET findings in 66-y-old man with mild cognitive impairment and cerebrospinal fluid values indicative of AD pathology. Axial slices of SUV ratio images are shown for 18F-AV-1451 and 18F-FDG PET. Global maximum intensities were set to 100 for scaling.

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Journal of Nuclear Medicine: 58 (9)
Journal of Nuclear Medicine
Vol. 58, Issue 9
September 1, 2017
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Is Tau Imaging More Than Just Upside-Down 18F-FDG Imaging?
Thilo van Eimeren, Gérard N. Bischof, Alexander Drzezga
Journal of Nuclear Medicine Sep 2017, 58 (9) 1357-1359; DOI: 10.2967/jnumed.117.190082

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Is Tau Imaging More Than Just Upside-Down 18F-FDG Imaging?
Thilo van Eimeren, Gérard N. Bischof, Alexander Drzezga
Journal of Nuclear Medicine Sep 2017, 58 (9) 1357-1359; DOI: 10.2967/jnumed.117.190082
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    • STATUS OF TRACER VALIDATION
    • POTENTIAL FOR EARLY DIAGNOSIS
    • POTENTIAL FOR DIFFERENTIAL DIAGNOSIS
    • POTENTIAL AS A BIOMARKER IN CLINICAL TRIALS
    • CONCLUSION
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