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Research ArticleOncology

TERT Promoter Mutation Predicts Radioiodine-Refractory Character in Distant Metastatic Differentiated Thyroid Cancer

Xue Yang, Jiao Li, Xiaoyi Li, Zhiyong Liang, Wen Gao, Jun Liang, Shujun Cheng and Yansong Lin
Journal of Nuclear Medicine February 2017, 58 (2) 258-265; DOI: https://doi.org/10.2967/jnumed.116.180240
Xue Yang
1Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Jiao Li
2Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Xiaoyi Li
3Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Zhiyong Liang
4Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; and
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Wen Gao
2Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Jun Liang
5Department of Medical Oncology, Peking University Cancer Hospital and Institute, Beijing, China
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Shujun Cheng
1Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Yansong Lin
2Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Article Information

vol. 58 no. 2 258-265
DOI 
https://doi.org/10.2967/jnumed.116.180240
PubMed 
27493271

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication June 24, 2016
  • Accepted for publication July 19, 2016
  • Published online February 1, 2017.

Article Versions

  • previous version (August 4, 2016 - 05:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Xue Yang1,
  2. Jiao Li2,
  3. Xiaoyi Li3,
  4. Zhiyong Liang4,
  5. Wen Gao2,
  6. Jun Liang5,
  7. Shujun Cheng*,1 and
  8. Yansong Lin*,2
  1. 1Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  2. 2Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  3. 3Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  4. 4Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; and
  5. 5Department of Medical Oncology, Peking University Cancer Hospital and Institute, Beijing, China
  1. For correspondence contact: Yansong Lin, Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing St., Dongcheng District, 100730, Beijing, China. E-mail: linys{at}pumch.cn
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Journal of Nuclear Medicine: 58 (2)
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TERT Promoter Mutation Predicts Radioiodine-Refractory Character in Distant Metastatic Differentiated Thyroid Cancer
Xue Yang, Jiao Li, Xiaoyi Li, Zhiyong Liang, Wen Gao, Jun Liang, Shujun Cheng, Yansong Lin
Journal of Nuclear Medicine Feb 2017, 58 (2) 258-265; DOI: 10.2967/jnumed.116.180240

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TERT Promoter Mutation Predicts Radioiodine-Refractory Character in Distant Metastatic Differentiated Thyroid Cancer
Xue Yang, Jiao Li, Xiaoyi Li, Zhiyong Liang, Wen Gao, Jun Liang, Shujun Cheng, Yansong Lin
Journal of Nuclear Medicine Feb 2017, 58 (2) 258-265; DOI: 10.2967/jnumed.116.180240
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Keywords

  • differentiated thyroid carcinoma
  • TERT mutation
  • radioactive iodine therapy
  • therapy response
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