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Journal of Nuclear Medicine

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Research ArticleOncology

Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and α-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts

Sharon K. Michelhaugh, Otto Muzik, Anthony R. Guastella, Neil V. Klinger, Lisa A. Polin, Hancheng Cai, Yangchun Xin, Thomas J. Mangner, Shaohui Zhang, Csaba Juhász and Sandeep Mittal
Journal of Nuclear Medicine February 2017, 58 (2) 208-213; DOI: https://doi.org/10.2967/jnumed.116.179994
Sharon K. Michelhaugh
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
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Otto Muzik
2Department of Pediatrics, Wayne State University, Detroit, Michigan
3Department of Radiology, Wayne State University, Detroit, Michigan
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
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Anthony R. Guastella
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
5Department of Oncology, Wayne State University, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
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Neil V. Klinger
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
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Lisa A. Polin
5Department of Oncology, Wayne State University, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
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Hancheng Cai
7Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern, Dallas, Texasand
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Yangchun Xin
7Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern, Dallas, Texasand
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Thomas J. Mangner
3Department of Radiology, Wayne State University, Detroit, Michigan
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
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Shaohui Zhang
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
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Csaba Juhász
2Department of Pediatrics, Wayne State University, Detroit, Michigan
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
8Department of Neurology, Wayne State University, Detroit, Michigan
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Sandeep Mittal
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
5Department of Oncology, Wayne State University, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
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Journal of Nuclear Medicine: 58 (2)
Journal of Nuclear Medicine
Vol. 58, Issue 2
February 1, 2017
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Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and α-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts
Sharon K. Michelhaugh, Otto Muzik, Anthony R. Guastella, Neil V. Klinger, Lisa A. Polin, Hancheng Cai, Yangchun Xin, Thomas J. Mangner, Shaohui Zhang, Csaba Juhász, Sandeep Mittal
Journal of Nuclear Medicine Feb 2017, 58 (2) 208-213; DOI: 10.2967/jnumed.116.179994

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Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and α-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts
Sharon K. Michelhaugh, Otto Muzik, Anthony R. Guastella, Neil V. Klinger, Lisa A. Polin, Hancheng Cai, Yangchun Xin, Thomas J. Mangner, Shaohui Zhang, Csaba Juhász, Sandeep Mittal
Journal of Nuclear Medicine Feb 2017, 58 (2) 208-213; DOI: 10.2967/jnumed.116.179994
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  • Glioblastoma
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