Research ArticleOncology
Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and α-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts
Sharon K. Michelhaugh, Otto Muzik, Anthony R. Guastella, Neil V. Klinger, Lisa A. Polin, Hancheng Cai, Yangchun Xin, Thomas J. Mangner, Shaohui Zhang, Csaba Juhász and Sandeep Mittal
Journal of Nuclear Medicine February 2017, 58 (2) 208-213; DOI: https://doi.org/10.2967/jnumed.116.179994
Sharon K. Michelhaugh
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
Otto Muzik
2Department of Pediatrics, Wayne State University, Detroit, Michigan
3Department of Radiology, Wayne State University, Detroit, Michigan
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
Anthony R. Guastella
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
5Department of Oncology, Wayne State University, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
Neil V. Klinger
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
Lisa A. Polin
5Department of Oncology, Wayne State University, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
Hancheng Cai
7Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern, Dallas, Texasand
Yangchun Xin
7Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern, Dallas, Texasand
Thomas J. Mangner
3Department of Radiology, Wayne State University, Detroit, Michigan
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
Shaohui Zhang
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
Csaba Juhász
2Department of Pediatrics, Wayne State University, Detroit, Michigan
4PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan
8Department of Neurology, Wayne State University, Detroit, Michigan
Sandeep Mittal
1Department of Neurosurgery, Wayne State University, Detroit, Michigan
5Department of Oncology, Wayne State University, Detroit, Michigan
6Karmanos Cancer Institute, Detroit, Michigan

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Journal of Nuclear Medicine
Vol. 58, Issue 2
February 1, 2017
Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and α-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts
Sharon K. Michelhaugh, Otto Muzik, Anthony R. Guastella, Neil V. Klinger, Lisa A. Polin, Hancheng Cai, Yangchun Xin, Thomas J. Mangner, Shaohui Zhang, Csaba Juhász, Sandeep Mittal
Journal of Nuclear Medicine Feb 2017, 58 (2) 208-213; DOI: 10.2967/jnumed.116.179994
Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and α-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts
Sharon K. Michelhaugh, Otto Muzik, Anthony R. Guastella, Neil V. Klinger, Lisa A. Polin, Hancheng Cai, Yangchun Xin, Thomas J. Mangner, Shaohui Zhang, Csaba Juhász, Sandeep Mittal
Journal of Nuclear Medicine Feb 2017, 58 (2) 208-213; DOI: 10.2967/jnumed.116.179994