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Research ArticleThe State of the Art

Validation of MRI Determination of the Penumbra by PET Measurements in Ischemic Stroke

Wolf-Dieter Heiss and Olivier Zaro Weber
Journal of Nuclear Medicine February 2017, 58 (2) 187-193; DOI: https://doi.org/10.2967/jnumed.116.185975
Wolf-Dieter Heiss
Max Planck Institute for Metabolism Research, Cologne, Germany
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Olivier Zaro Weber
Max Planck Institute for Metabolism Research, Cologne, Germany
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Article Information

vol. 58 no. 2 187-193
DOI 
https://doi.org/10.2967/jnumed.116.185975
PubMed 
27879370

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication November 10, 2016
  • Accepted for publication November 10, 2016
  • Published online February 1, 2017.

Article Versions

  • previous version (November 22, 2016 - 12:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Wolf-Dieter Heiss and
  2. Olivier Zaro Weber
  1. Max Planck Institute for Metabolism Research, Cologne, Germany
  1. For correspondence or reprints contact: Wolf-Dieter Heiss, Max Planck Institute for Neurological Research, Gleueler Strasse 50, 50931 Köln, Germany. E-mail: wdh{at}nf.mpg.de
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Journal of Nuclear Medicine: 58 (2)
Journal of Nuclear Medicine
Vol. 58, Issue 2
February 1, 2017
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Validation of MRI Determination of the Penumbra by PET Measurements in Ischemic Stroke
Wolf-Dieter Heiss, Olivier Zaro Weber
Journal of Nuclear Medicine Feb 2017, 58 (2) 187-193; DOI: 10.2967/jnumed.116.185975

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Validation of MRI Determination of the Penumbra by PET Measurements in Ischemic Stroke
Wolf-Dieter Heiss, Olivier Zaro Weber
Journal of Nuclear Medicine Feb 2017, 58 (2) 187-193; DOI: 10.2967/jnumed.116.185975
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Jump to section

  • Article
    • Abstract
    • ENERGY REQUIREMENTS OF BRAIN TISSUE
    • FLOW THRESHOLDS FOR PRESERVATION OF FUNCTION AND MORPHOLOGIC INTEGRITY
    • PROGRESSION OF ISCHEMIC TISSUE DAMAGE
    • IDENTIFICATION OF PENUMBRA BY IMAGING
    • MRI MISMATCH AS SURROGATE FOR PENUMBRA
    • VALIDATION OF MRI SIGNATURES BY PET MEASUREMENTS
    • PENUMBRA AS SURROGATE MARKER FOR TREATMENT EFFICACY
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
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Keywords

  • penumbra
  • Flow Thresholds
  • Core of infarction
  • neuronal activity
  • PET
  • PWI–DWI mismatch
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