Quantitative Analysis of Dynamic 123I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method

Jing Wu; Shu-fei Lin; Jean-Dominique Gallezot; Chung Chan; Rameshwar Prasad; Stephanie L. Thorn; Mitchel R. Stacy; Yiyun Huang; Taraneh Hashemi Zonouz; Yi-Hwa Liu; Rachel J. Lampert; Richard E. Carson; Albert J. Sinusas; Chi Liu

doi:10.2967/jnumed.115.171710

Research ArticleClinical Investigations

Quantitative Analysis of Dynamic ¹²³I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method

Jing Wu, Shu-fei Lin, Jean-Dominique Gallezot, Chung Chan, Rameshwar Prasad, Stephanie L. Thorn, Mitchel R. Stacy, Yiyun Huang, Taraneh Hashemi Zonouz, Yi-Hwa Liu, Rachel J. Lampert, Richard E. Carson, Albert J. Sinusas and Chi Liu

Journal of Nuclear Medicine August 2016, 57 (8) 1226-1232; DOI: https://doi.org/10.2967/jnumed.115.171710

Jing Wu

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Shu-fei Lin

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Jean-Dominique Gallezot

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Chung Chan

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Rameshwar Prasad

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Stephanie L. Thorn

2Department of Internal Medicine (Cardiology), Yale University, New Haven, Connecticut

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Mitchel R. Stacy

2Department of Internal Medicine (Cardiology), Yale University, New Haven, Connecticut

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Yiyun Huang

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Taraneh Hashemi Zonouz

2Department of Internal Medicine (Cardiology), Yale University, New Haven, Connecticut

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Yi-Hwa Liu

2Department of Internal Medicine (Cardiology), Yale University, New Haven, Connecticut

3Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; and

4Department of Biomedical Engineering, Chung Yuan Christian University, Taoyuan, Taiwan

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Rachel J. Lampert

2Department of Internal Medicine (Cardiology), Yale University, New Haven, Connecticut

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Richard E. Carson

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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Albert J. Sinusas

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

2Department of Internal Medicine (Cardiology), Yale University, New Haven, Connecticut

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Chi Liu

1Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut

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August 1, 2016

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Quantitative Analysis of Dynamic ¹²³I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method

Journal of Nuclear Medicine Aug 2016, 57 (8) 1226-1232; DOI: 10.2967/jnumed.115.171710

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Quantitative Analysis of Dynamic ¹²³I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method

Journal of Nuclear Medicine Aug 2016, 57 (8) 1226-1232; DOI: 10.2967/jnumed.115.171710

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Keywords

Dynamic 123I-metaiodobenzylguanidine SPECT imaging
metabolite correction
kinetic modeling

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