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Research ArticleClinical Investigations

DNA Damage in Peripheral Blood Lymphocytes of Thyroid Cancer Patients After Radioiodine Therapy

Uta Eberlein, Harry Scherthan, Christina Bluemel, Michel Peper, Constantin Lapa, Andreas Konrad Buck, Matthias Port and Michael Lassmann
Journal of Nuclear Medicine February 2016, 57 (2) 173-179; DOI: https://doi.org/10.2967/jnumed.115.164814
Uta Eberlein
1Department of Nuclear Medicine, University of Würzburg, Germany; and
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Harry Scherthan
2Bundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany
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Christina Bluemel
1Department of Nuclear Medicine, University of Würzburg, Germany; and
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Michel Peper
2Bundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany
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Constantin Lapa
1Department of Nuclear Medicine, University of Würzburg, Germany; and
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Andreas Konrad Buck
1Department of Nuclear Medicine, University of Würzburg, Germany; and
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Matthias Port
2Bundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany
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Michael Lassmann
1Department of Nuclear Medicine, University of Würzburg, Germany; and
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Article Information

vol. 57 no. 2 173-179
DOI 
https://doi.org/10.2967/jnumed.115.164814
PubMed 
26564321

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication July 31, 2015
  • Accepted for publication October 28, 2015
  • Published online February 1, 2016.

Article Versions

  • previous version (November 12, 2015 - 06:51).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Uta Eberlein*,1,
  2. Harry Scherthan*,2,
  3. Christina Bluemel1,
  4. Michel Peper2,
  5. Constantin Lapa1,
  6. Andreas Konrad Buck1,
  7. Matthias Port2 and
  8. Michael Lassmann1
  1. 1Department of Nuclear Medicine, University of Würzburg, Germany; and
  2. 2Bundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany
  1. For correspondence or reprints contact: Michael Lassmann, Department of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Strasse 6, 97080 Würzburg, Germany. E-mail: Lassmann_m{at}ukw.de
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Journal of Nuclear Medicine: 57 (2)
Journal of Nuclear Medicine
Vol. 57, Issue 2
February 1, 2016
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DNA Damage in Peripheral Blood Lymphocytes of Thyroid Cancer Patients After Radioiodine Therapy
Uta Eberlein, Harry Scherthan, Christina Bluemel, Michel Peper, Constantin Lapa, Andreas Konrad Buck, Matthias Port, Michael Lassmann
Journal of Nuclear Medicine Feb 2016, 57 (2) 173-179; DOI: 10.2967/jnumed.115.164814

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DNA Damage in Peripheral Blood Lymphocytes of Thyroid Cancer Patients After Radioiodine Therapy
Uta Eberlein, Harry Scherthan, Christina Bluemel, Michel Peper, Constantin Lapa, Andreas Konrad Buck, Matthias Port, Michael Lassmann
Journal of Nuclear Medicine Feb 2016, 57 (2) 173-179; DOI: 10.2967/jnumed.115.164814
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Keywords

  • γ-H2AX
  • 53BP1
  • biological dosimetry
  • radioiodine therapy
  • DTC
  • absorbed dose to blood
  • dose response
  • DSB focus assay
  • DNA damage
  • 131I
  • differentiated thyroid cancer
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