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Journal of Nuclear Medicine

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Research ArticleClinical Investigations

Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1–Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging

Rahul Dimber, Qi Guo, Courtney Bishop, Adine Adonis, Aisling Buckley, Agnes Kocsis, David Owen, Nicola Kalk, Rexford Newbould, Roger N. Gunn, Eugenii A. Rabiner and Graham P. Taylor
Journal of Nuclear Medicine December 2016, 57 (12) 1905-1912; DOI: https://doi.org/10.2967/jnumed.116.175083
Rahul Dimber
1Imanova, Centre for Imaging Sciences, London, United Kingdom
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Qi Guo
2Institute of Psychiatry, King’s College London, London, United Kingdom
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Courtney Bishop
1Imanova, Centre for Imaging Sciences, London, United Kingdom
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Adine Adonis
3National Centre for Human Retrovirology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
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Aisling Buckley
4Department of Clinical Health Psychology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom; and
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Agnes Kocsis
4Department of Clinical Health Psychology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom; and
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David Owen
5Division of Brain Sciences, Imperial College London, London, United Kingdom
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Nicola Kalk
5Division of Brain Sciences, Imperial College London, London, United Kingdom
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Rexford Newbould
1Imanova, Centre for Imaging Sciences, London, United Kingdom
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Roger N. Gunn
1Imanova, Centre for Imaging Sciences, London, United Kingdom
5Division of Brain Sciences, Imperial College London, London, United Kingdom
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Eugenii A. Rabiner
1Imanova, Centre for Imaging Sciences, London, United Kingdom
2Institute of Psychiatry, King’s College London, London, United Kingdom
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Graham P. Taylor
3National Centre for Human Retrovirology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
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Journal of Nuclear Medicine: 57 (12)
Journal of Nuclear Medicine
Vol. 57, Issue 12
December 1, 2016
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Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1–Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging
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Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1–Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging
Rahul Dimber, Qi Guo, Courtney Bishop, Adine Adonis, Aisling Buckley, Agnes Kocsis, David Owen, Nicola Kalk, Rexford Newbould, Roger N. Gunn, Eugenii A. Rabiner, Graham P. Taylor
Journal of Nuclear Medicine Dec 2016, 57 (12) 1905-1912; DOI: 10.2967/jnumed.116.175083

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Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1–Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging
Rahul Dimber, Qi Guo, Courtney Bishop, Adine Adonis, Aisling Buckley, Agnes Kocsis, David Owen, Nicola Kalk, Rexford Newbould, Roger N. Gunn, Eugenii A. Rabiner, Graham P. Taylor
Journal of Nuclear Medicine Dec 2016, 57 (12) 1905-1912; DOI: 10.2967/jnumed.116.175083
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Keywords

  • HTLV1
  • HAM
  • neuroinflammation
  • MRI
  • DWI
  • PET
  • [11C] PBR28
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