Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An 18F-FPEB PET Study

Gil Leurquin-Sterk; Jan Van den Stock; Cleo Lina Crunelle; Bart de Laat; Akila Weerasekera; Uwe Himmelreich; Guy Bormans; Koen Van Laere

doi:10.2967/jnumed.116.176032

Research ArticleClinical Investigations

Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An ¹⁸F-FPEB PET Study

Gil Leurquin-Sterk, Jan Van den Stock, Cleo Lina Crunelle, Bart de Laat, Akila Weerasekera, Uwe Himmelreich, Guy Bormans and Koen Van Laere

Journal of Nuclear Medicine November 2016, 57 (11) 1746-1752; DOI: https://doi.org/10.2967/jnumed.116.176032

Gil Leurquin-Sterk

1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium

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Jan Van den Stock

2Laboratory for Translational Neuropsychiatry, Department of Neurosciences, KU Leuven and Department of Old Age Psychiatry, University Hospitals Leuven, Leuven, Belgium

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Cleo Lina Crunelle

3Toxicological Center, University of Antwerp, Wilrijk, Belgium

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Bart de Laat

1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium

4MoSAIC, Molecular Small Animal Imaging Center, KU Leuven, Leuven, Belgium

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Akila Weerasekera

5Biomedical MRI/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium; and

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Uwe Himmelreich

5Biomedical MRI/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium; and

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Guy Bormans

6Laboratory for Radiopharmacy, KU Leuven, Leuven, Belgium

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Koen Van Laere

1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium

4MoSAIC, Molecular Small Animal Imaging Center, KU Leuven, Leuven, Belgium

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Journal of Nuclear Medicine

Vol. 57, Issue 11

November 1, 2016

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Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An ¹⁸F-FPEB PET Study

Gil Leurquin-Sterk, Jan Van den Stock, Cleo Lina Crunelle, Bart de Laat, Akila Weerasekera, Uwe Himmelreich, Guy Bormans, Koen Van Laere

Journal of Nuclear Medicine Nov 2016, 57 (11) 1746-1752; DOI: 10.2967/jnumed.116.176032

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Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An ¹⁸F-FPEB PET Study

Gil Leurquin-Sterk, Jan Van den Stock, Cleo Lina Crunelle, Bart de Laat, Akila Weerasekera, Uwe Himmelreich, Guy Bormans, Koen Van Laere

Journal of Nuclear Medicine Nov 2016, 57 (11) 1746-1752; DOI: 10.2967/jnumed.116.176032

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Keywords

neuroimaging
18F-FPEB
mGluR5
Personality
novelty seeking

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