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Research ArticleClinical Investigations

Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An 18F-FPEB PET Study

Gil Leurquin-Sterk, Jan Van den Stock, Cleo Lina Crunelle, Bart de Laat, Akila Weerasekera, Uwe Himmelreich, Guy Bormans and Koen Van Laere
Journal of Nuclear Medicine November 2016, 57 (11) 1746-1752; DOI: https://doi.org/10.2967/jnumed.116.176032
Gil Leurquin-Sterk
1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium
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Jan Van den Stock
2Laboratory for Translational Neuropsychiatry, Department of Neurosciences, KU Leuven and Department of Old Age Psychiatry, University Hospitals Leuven, Leuven, Belgium
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Cleo Lina Crunelle
3Toxicological Center, University of Antwerp, Wilrijk, Belgium
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Bart de Laat
1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium
4MoSAIC, Molecular Small Animal Imaging Center, KU Leuven, Leuven, Belgium
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Akila Weerasekera
5Biomedical MRI/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium; and
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Uwe Himmelreich
5Biomedical MRI/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium; and
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Guy Bormans
6Laboratory for Radiopharmacy, KU Leuven, Leuven, Belgium
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Koen Van Laere
1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium
4MoSAIC, Molecular Small Animal Imaging Center, KU Leuven, Leuven, Belgium
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Article Information

vol. 57 no. 11 1746-1752
DOI 
https://doi.org/10.2967/jnumed.116.176032
PubMed 
27283933

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication March 21, 2016
  • Accepted for publication May 6, 2016
  • Published online November 1, 2016.

Article Versions

  • previous version (June 9, 2016 - 10:28).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Gil Leurquin-Sterk1,
  2. Jan Van den Stock2,
  3. Cleo Lina Crunelle3,
  4. Bart de Laat1,4,
  5. Akila Weerasekera5,
  6. Uwe Himmelreich5,
  7. Guy Bormans6 and
  8. Koen Van Laere1,4
  1. 1Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium
  2. 2Laboratory for Translational Neuropsychiatry, Department of Neurosciences, KU Leuven and Department of Old Age Psychiatry, University Hospitals Leuven, Leuven, Belgium
  3. 3Toxicological Center, University of Antwerp, Wilrijk, Belgium
  4. 4MoSAIC, Molecular Small Animal Imaging Center, KU Leuven, Leuven, Belgium
  5. 5Biomedical MRI/MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium; and
  6. 6Laboratory for Radiopharmacy, KU Leuven, Leuven, Belgium
  1. For correspondence or reprints contact: Gil Leurquin-Sterk, Division of Nuclear Medicine, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium. E-mail: gil.leurquin-sterk{at}uzleuven.be
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Journal of Nuclear Medicine: 57 (11)
Journal of Nuclear Medicine
Vol. 57, Issue 11
November 1, 2016
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Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An 18F-FPEB PET Study
Gil Leurquin-Sterk, Jan Van den Stock, Cleo Lina Crunelle, Bart de Laat, Akila Weerasekera, Uwe Himmelreich, Guy Bormans, Koen Van Laere
Journal of Nuclear Medicine Nov 2016, 57 (11) 1746-1752; DOI: 10.2967/jnumed.116.176032

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Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An 18F-FPEB PET Study
Gil Leurquin-Sterk, Jan Van den Stock, Cleo Lina Crunelle, Bart de Laat, Akila Weerasekera, Uwe Himmelreich, Guy Bormans, Koen Van Laere
Journal of Nuclear Medicine Nov 2016, 57 (11) 1746-1752; DOI: 10.2967/jnumed.116.176032
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Keywords

  • neuroimaging
  • 18F-FPEB
  • mGluR5
  • Personality
  • novelty seeking
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