Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Research ArticleBasic Science Investigations

Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation

Shichun Peng, Yilong Ma, Joseph Flores, Michael Cornfeldt, Branka Mitrovic, David Eidelberg and Doris J. Doudet
Journal of Nuclear Medicine October 2016, 57 (10) 1591-1598; DOI: https://doi.org/10.2967/jnumed.115.161513
Shichun Peng
1Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, New York, New York
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yilong Ma
1Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, New York, New York
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joseph Flores
2Department of Neurology, University of British Columbia, Vancouver, British Columbia, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Cornfeldt
3Titan Pharmaceuticals Inc., Somerville, New Jersey; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Branka Mitrovic
4Bayer HealthCare Pharmaceuticals Inc., Richmond, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David Eidelberg
1Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, New York, New York
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Doris J. Doudet
2Department of Neurology, University of British Columbia, Vancouver, British Columbia, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF
Loading

Article Information

vol. 57 no. 10 1591-1598
DOI 
https://doi.org/10.2967/jnumed.115.161513
PubMed 
27056614

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication July 7, 2015
  • Accepted for publication March 7, 2016
  • Published online October 3, 2016.

Article Versions

  • previous version (April 7, 2016 - 05:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Shichun Peng*,1,
  2. Yilong Ma*,1,
  3. Joseph Flores2,
  4. Michael Cornfeldt3,
  5. Branka Mitrovic4,
  6. David Eidelberg†,1 and
  7. Doris J. Doudet†,2
  1. 1Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, New York, New York
  2. 2Department of Neurology, University of British Columbia, Vancouver, British Columbia, Canada
  3. 3Titan Pharmaceuticals Inc., Somerville, New Jersey; and
  4. 4Bayer HealthCare Pharmaceuticals Inc., Richmond, California
  1. For correspondence or reprints contact: Yilong Ma, The Feinstein Institute for Medical Research, 350 Community Dr., Manhasset, NY 11030. E-mail: yma{at}nshs.edu
View Full Text

Statistics from Altmetric.com

Cited By...

  • 14 Citations
  • 18 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Network imaging biomarkers: insights and clinical applications in Parkinson's disease
    Katharina A Schindlbeck, David Eidelberg
    The Lancet Neurology 2018 17 7
  • Abnormal metabolic brain network associated with Parkinson’s disease: replication on a new European sample
    Petra Tomše, Luka Jensterle, Marko Grmek, Katja Zaletel, Zvezdan Pirtošek, Vijay Dhawan, Shichun Peng, David Eidelberg, Yilong Ma, Maja Trošt
    Neuroradiology 2017 59 5
  • Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia
    Renata P. Lerner, Veronica Francardo, Koji Fujita, Zisis Bimpisidis, Vincent A. Jourdain, Chris C. Tang, Stephen L. Dewey, Thomas Chaly, M. Angela Cenci, David Eidelberg
    Scientific Reports 2017 7 1
  • Dynamic 18F-FPCIT PET: Quantification of Parkinson Disease Metabolic Networks and Nigrostriatal Dopaminergic Dysfunction in a Single Imaging Session
    Shichun Peng, Chris Tang, Katharina Schindlbeck, Yaacov Rydzinski, Vijay Dhawan, Phoebe G. Spetsieris, Yilong Ma, David Eidelberg
    Journal of Nuclear Medicine 2021 62 12
  • Network Structure and Function in Parkinson’s Disease
    Ji Hyun Ko, Phoebe G Spetsieris, David Eidelberg
    Cerebral Cortex 2017
  • Comparative test-retest variability of outcome parameters derived from brain [18F]FDG PET studies in non-human primates
    Sébastien Goutal, Nicolas Tournier, Martine Guillermier, Nadja Van Camp, Olivier Barret, Mylène Gaudin, Michel Bottlaender, Philippe Hantraye, Sonia Lavisse, Matteo Bauckneht
    PLOS ONE 2020 15 10
  • Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease
    Jelena Osmanovic Barilar, Ana Knezovic, Ana Babic Perhoc, Jan Homolak, Peter Riederer, Melita Salkovic-Petrisic
    Journal of Neural Transmission 2020 127 2
  • Neuroimaging evaluation of deep brain stimulation in the treatment of representative neurodegenerative and neuropsychiatric disorders
    Shichun Peng, Vijay Dhawan, David Eidelberg, Yilong Ma
    Bioelectronic Medicine 2021 7 1
  • Clinical considerations in Parkinson’s disease cell therapy
    Jun Xue, Yifan Wu, Yuting Bao, Minglai Zhao, Fangzhou Li, Jing Sun, Yimin Sun, Jian Wang, Liang Chen, Ying Mao, Jeffrey S. Schweitzer, Bin Song
    Ageing Research Reviews 2023 83
  • Selecting the Best Animal Model of Parkinson’s Disease for Your Research Purpose: Insight from in vivo PET Imaging Studies
    Caroline Cristiano Real, Karina Henrique Binda, Majken Borup Thomsen, Thea Pinholt Lillethorup, David James Brooks, Anne Marlene Landau
    Current Neuropharmacology 2023 21 5

Article usage

Article usage: April 2016 to April 2025

AbstractFullPdf
Apr 2016411037
May 2016219010
Jun 20169402
Jul 20166102
Aug 20165305
Sep 20165604
Oct 2016605532
Nov 2016145411
Dec 201610908
Jan 20179867
Feb 20174000
Mar 20177127
Apr 20173835
May 201747118
Jun 20173531
Jul 201729510
Aug 201731311
Sep 20173238
Oct 20172832
Nov 20173346
Dec 20172383
Jan 20181828
Feb 201829308
Mar 2018281511
Apr 20182983
May 20182443
Jun 20181741
Jul 20181351
Aug 20182043
Sep 20181225
Oct 20181364
Nov 20181210
Dec 2018843
Jan 20191412
Feb 20191343
Mar 2019765
Apr 2019634
May 20191866
Jun 2019626
Jul 201914310
Aug 2019811
Sep 201914511
Oct 201919610
Nov 201911110
Dec 201913611
Jan 20201888
Feb 2020632
Mar 20201138
Apr 202012117
May 202014913
Jun 2020805
Jul 202012420
Aug 2020994
Sep 20202032
Oct 202014813
Nov 20201127
Dec 202010815
Jan 20215712
Feb 2021111411
Mar 2021263
Apr 20214136
May 20214214
Jun 20217105
Jul 202151015
Aug 2021657
Sep 20216209
Oct 20212619
Nov 20215720
Dec 202162611
Jan 2022796
Feb 20229911
Mar 2022062
Apr 20227103
May 202281213
Jun 2022587
Jul 202222821
Aug 20225138
Sep 202221010
Oct 2022377
Nov 2022389
Dec 20222119
Jan 202336710
Feb 20234157
Mar 2023694
Apr 20233144
May 2023489
Jun 202301310
Jul 20235139
Aug 2023567
Sep 2023086
Oct 20236910
Nov 20231106
Dec 20232233
Jan 20246132
Feb 2024264
Mar 202431327
Apr 202453010
May 20242315
Jun 20245126
Jul 2024117222
Aug 2024176929
Sep 202482818
Oct 20244198
Nov 20247611
Dec 202422710
Jan 202571625
Feb 202576521
Mar 202553218
Apr 202563431
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine: 57 (10)
Journal of Nuclear Medicine
Vol. 57, Issue 10
October 1, 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation
Shichun Peng, Yilong Ma, Joseph Flores, Michael Cornfeldt, Branka Mitrovic, David Eidelberg, Doris J. Doudet
Journal of Nuclear Medicine Oct 2016, 57 (10) 1591-1598; DOI: 10.2967/jnumed.115.161513

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation
Shichun Peng, Yilong Ma, Joseph Flores, Michael Cornfeldt, Branka Mitrovic, David Eidelberg, Doris J. Doudet
Journal of Nuclear Medicine Oct 2016, 57 (10) 1591-1598; DOI: 10.2967/jnumed.115.161513
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSION
    • DISCLOSURE
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF

Related Articles

  • Reverse Translation in Parkinson Disease
  • This Month in JNM
  • PubMed
  • Google Scholar

Cited By...

  • Dynamic 18F-FPCIT PET: Quantification of Parkinson Disease Metabolic Networks and Nigrostriatal Dopaminergic Dysfunction in a Single Imaging Session
  • Induced Cognitive Impairments Reversed by Grafts of Neural Precursors: a Longitudinal Study in a Macaque Model of Parkinsons Disease
  • Reverse Translation in Parkinson Disease
  • Google Scholar

More in this TOC Section

  • Design and Fabrication of Kidney Phantoms for Internal Radiation Dosimetry Using 3D Printing Technology
  • Synthesis and Biologic Evaluation of Novel 18F-Labeled Probes Targeting Prostate-Specific Membrane Antigen for PET of Prostate Cancer
  • Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers
Show more Basic Science Investigations

Similar Articles

Keywords

  • parkinsonism
  • primate model
  • FDG PET
  • network analysis
  • dopamine cell transplantation
  • retinal pigment epithelial cell
SNMMI

© 2025 SNMMI

Powered by HighWire