Article Figures & Data
Figures
- FIGURE 1.
Characterization of 31 patients with pancreatic cysts. Twenty-two patients were operated on, and 9 patients were followed up. Histopathologic findings of operated patients are also shown. MCN = mucinous cystic neoplasia; MD = main duct; NET = neuroendocrine tumor; PC = pseudocysts; PDAC = pancreatic ductal adenocarcinoma; SCN = serous cystic neoplasia; SPT = solid pseudopapillary tumor. *One patient with severe dysplasia in resection margin. #Three-branch-duct IPMN. §One-branch-duct IPMN and 2 undifferentiated lesions.
- FIGURE 2.
Distributions of SUVmax in benign and malignant cystic pancreatic lesions.
- FIGURE 3.
(A and B) Enhanced MDCT image (A) and enhanced T1-weighted MR image (B) of patient with lesion in tail of pancreas (arrows). Both MDCT and MR imaging had findings suggestive of malignancy. (C) Focal uptake was observed on 18F-FDG PET/CT (arrows). Histopathology confirmed adenocarcinoma.
- FIGURE 4.
46-y-old man with abdominal pain for 1 mo, significant weight loss, and jaundice. He had neither previous episodes of pancreatitis nor excess alcohol consumption. (A) MDCT showed thick-walled cystic mass enhancing with contrast in head of pancreas (arrows). ERCP showed biliary stricture, and stent was placed. Serum Ca19-9 activity was slightly elevated (51 kU/L). (B) T1-weighted enhanced MR imaging showed thick, irregular walls containing cystic lesion suspected of being malignant (arrows). (C) 18F-FDG PET/CT showed only diffuse uptake throughout pancreas. Patient underwent pancreaticoduodenectomy, and histopathology revealed pseudocyst (7 cm).
- FIGURE 5.
Corresponding MDCT (A), MR (B), and PET/CT (C) images of patient with 3-cm cystic lesion in head of pancreas (arrows). Both MDCT and MR imaging were suggestive of malignancy. No uptake was observed on 18F-FDG PET/CT. During 18 mo of follow-up, patient was asymptomatic.
Tables
Parameter Total (n = 31) Malignant (n = 6) Benign (n = 25) P Mean age ± SD (y) 57.1 ± 14.5 60.8 ± 16.3 56.2 ± 14.2 NS Sex (F/M) 19/12 3/3 16/9 NS Body mass index (kg/m2) 25.0 ± 4.1 23.9 ± 2.8 25.5 ± 4.3 NS Use of alcohol (yes/no) 2/29 0/6 2/23 NS Smoking (yes/no) 6/25 1/5 5/20 NS History of pancreatitis (yes/no) 6/25 0/6 2/23 NS Symptoms (yes/no) 19/12 5/1 14/11 NS Blood chemistry Ca19-9 (kU/L) 87 ± 263 232 ± 494 47 ± 156* NS Carcinoembryonic antigen (μg/L) 2.6 ± 1.6 3.0 ± 2.3 2.5 ± 1.4 NS Total bilirubin (μmol/L) 11.9 ± 10.3 9.7 ± 2.6 12.8 ± 11.6 NS Alkaline phosphatase (U/L) 70 ± 32 76 ± 50 68 ± 28 NS Alanine transferase (U/L) 25 ± 18 28 ± 28 24 ± 15 NS Amylase (U/L) 69 ± 31 53 ± 24 74 ± 32 NS γ-glutamyl transferase (U/L) 45 ± 62 42 ± 28 46 ± 68 NS Location Head 15 2 13 NS Body 5 1 4 NS Tail 8 2 6 NS Whole pancreas 3 1 2† NS Size† (cm) NS Mean ± SD 5.3 ± 3.8 5.1 ± 4.0 4.8 ± 2.7 Range 1.3–18 2.5–18 1.3–10
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