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Research ArticlePET/MR Imaging: Potential Clinical and Research Applications

PET/MR in Oncology: Non–18F-FDG Tracers for Routine Applications

Isabel Rauscher, Matthias Eiber, Michael Souvatzoglou, Markus Schwaiger and Ambros J. Beer
Journal of Nuclear Medicine June 2014, 55 (Supplement 2) 25S-31S; DOI: https://doi.org/10.2967/jnumed.113.129536
Isabel Rauscher
1German Cancer Consortium (DKTK), Heidelberg, Germany
2Department of Nuclear Medicine, Technische Universität München, Munich, Germany
3German Cancer Research Center (DKFZ), Heidelberg, Germany; and
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Matthias Eiber
2Department of Nuclear Medicine, Technische Universität München, Munich, Germany
4Department of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany
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Michael Souvatzoglou
2Department of Nuclear Medicine, Technische Universität München, Munich, Germany
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Markus Schwaiger
2Department of Nuclear Medicine, Technische Universität München, Munich, Germany
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Ambros J. Beer
2Department of Nuclear Medicine, Technische Universität München, Munich, Germany
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    FIGURE 1.

    Simultaneously acquired 68Ga-DOTATOC PET/CT and PET/MR images in 41-y-old patient with biopsy-proven NET of pancreas (dotted arrow) and liver metastasis in lateral fifth segment of liver (solid arrow) are shown. PET part of PET/MR (A), PET/MR (B), and PET/CT (F) images show intense focal 68Ga-DOTATOC uptake in pancreatic head and location of liver metastasis. In corresponding CT scan, liver metastasis can be clearly identified, with its peripheral arterial contrast enhancement (C), whereas identification of primary tumor in pancreatic head is difficult. In corresponding MR images, there is intense arterial hyperperfusion of liver metastasis and pancreatic head in dynamic GRE sequence (D) and low apparent diffusion coefficient values both in pancreatic head and in location of liver metastasis, indicating diffusion restriction (E).

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    FIGURE 2.

    Axial 68Ga-PSMA PET/MR images of 63-y-old patient with recurrent prostate cancer with hypointense signal alterations in T2w images (A, arrow) and intense focal 68Ga-PSMA uptake in right seminal vesicle of PET part of PET/MR (B, arrow) and in fused PET with T2w images (C arrow).

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    FIGURE 3.

    CT and 18F-fluoride PET/MR images of 64-y-old patient with prostate cancer and bone metastases with coronal CT images (A, arrow), coronal T2 short τ inversion recovery (B, arrow), and T1 TSE (C, arrow). PET of PET/MR shows intense focal 18F-fluoride uptake (D, arrow) whereas fused 18F-fluoride PET image with simultaneously acquired T1 TSE image (E) demonstrates concordance of metabolic and anatomic imaging.

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Journal of Nuclear Medicine: 55 (Supplement 2)
Journal of Nuclear Medicine
Vol. 55, Issue Supplement 2
June 1, 2014
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PET/MR in Oncology: Non–18F-FDG Tracers for Routine Applications
Isabel Rauscher, Matthias Eiber, Michael Souvatzoglou, Markus Schwaiger, Ambros J. Beer
Journal of Nuclear Medicine Jun 2014, 55 (Supplement 2) 25S-31S; DOI: 10.2967/jnumed.113.129536

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PET/MR in Oncology: Non–18F-FDG Tracers for Routine Applications
Isabel Rauscher, Matthias Eiber, Michael Souvatzoglou, Markus Schwaiger, Ambros J. Beer
Journal of Nuclear Medicine Jun 2014, 55 (Supplement 2) 25S-31S; DOI: 10.2967/jnumed.113.129536
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Keywords

  • PET/MR
  • non–18F-FDG
  • oncology
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