18F-MCL-524, an 18F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study

Sjoerd J. Finnema; Vladimir Stepanov; Ryuji Nakao; Anna W. Sromek; Tangzhi Zhang; John L. Neumeyer; Susan R. George; Philip Seeman; Michael G. Stabin; Cathrine Jonsson; Lars Farde; Christer Halldin

doi:10.2967/jnumed.113.133876

Research ArticleBasic Science Investigations

¹⁸F-MCL-524, an ¹⁸F-Labeled Dopamine D₂ and D₃ Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study

Sjoerd J. Finnema, Vladimir Stepanov, Ryuji Nakao, Anna W. Sromek, Tangzhi Zhang, John L. Neumeyer, Susan R. George, Philip Seeman, Michael G. Stabin, Cathrine Jonsson, Lars Farde and Christer Halldin

Journal of Nuclear Medicine July 2014, 55 (7) 1164-1170; DOI: https://doi.org/10.2967/jnumed.113.133876

Sjoerd J. Finnema

1Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden

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Vladimir Stepanov

1Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden

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Ryuji Nakao

1Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden

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Anna W. Sromek

2McLean Hospital, Harvard Medical School, Belmont, Massachusetts

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Tangzhi Zhang

2McLean Hospital, Harvard Medical School, Belmont, Massachusetts

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John L. Neumeyer

2McLean Hospital, Harvard Medical School, Belmont, Massachusetts

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Susan R. George

3University of Toronto, Toronto, Ontario, Canada

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Philip Seeman

3University of Toronto, Toronto, Ontario, Canada

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Michael G. Stabin

4Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee

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Cathrine Jonsson

5Department of Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden; and

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Lars Farde

1Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden

6AstraZeneca, Translational Science Center at Karolinska Institutet, Stockholm, Sweden

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Christer Halldin

1Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden

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Journal of Nuclear Medicine

Vol. 55, Issue 7

July 1, 2014

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¹⁸F-MCL-524, an ¹⁸F-Labeled Dopamine D₂ and D₃ Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study

Sjoerd J. Finnema, Vladimir Stepanov, Ryuji Nakao, Anna W. Sromek, Tangzhi Zhang, John L. Neumeyer, Susan R. George, Philip Seeman, Michael G. Stabin, Cathrine Jonsson, Lars Farde, Christer Halldin

Journal of Nuclear Medicine Jul 2014, 55 (7) 1164-1170; DOI: 10.2967/jnumed.113.133876

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¹⁸F-MCL-524, an ¹⁸F-Labeled Dopamine D₂ and D₃ Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study

Sjoerd J. Finnema, Vladimir Stepanov, Ryuji Nakao, Anna W. Sromek, Tangzhi Zhang, John L. Neumeyer, Susan R. George, Philip Seeman, Michael G. Stabin, Cathrine Jonsson, Lars Farde, Christer Halldin

Journal of Nuclear Medicine Jul 2014, 55 (7) 1164-1170; DOI: 10.2967/jnumed.113.133876

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18F-MCL-524
agonist
dopamine
monkey
PET

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¹⁸F-MCL-524, an ¹⁸F-Labeled Dopamine D₂ and D₃ Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study

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