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Journal of Nuclear Medicine

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Research ArticleBasic Science Investigations

Integrin αvβ6–Targeted SPECT Imaging for Pancreatic Cancer Detection

Zhaofei Liu, Hao Liu, Teng Ma, Xianlei Sun, Jiyun Shi, Bing Jia, Yi Sun, Jun Zhan, Hongquan Zhang, Zhaohui Zhu and Fan Wang
Journal of Nuclear Medicine June 2014, 55 (6) 989-994; DOI: https://doi.org/10.2967/jnumed.113.132969
Zhaofei Liu
1Medical Isotopes Research Center, Peking University, Beijing, China
2Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China
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Hao Liu
1Medical Isotopes Research Center, Peking University, Beijing, China
2Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China
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Teng Ma
1Medical Isotopes Research Center, Peking University, Beijing, China
2Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China
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Xianlei Sun
1Medical Isotopes Research Center, Peking University, Beijing, China
2Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China
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Jiyun Shi
1Medical Isotopes Research Center, Peking University, Beijing, China
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Bing Jia
1Medical Isotopes Research Center, Peking University, Beijing, China
2Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China
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Yi Sun
3Department of Nuclear Medicine, Peking Union Medical College Hospital, Beijing, China
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Jun Zhan
4Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Beijing, China
5Laboratory of Molecular Cell Biology and Tumor Biology, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, China; and
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Hongquan Zhang
4Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Beijing, China
5Laboratory of Molecular Cell Biology and Tumor Biology, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, China; and
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Zhaohui Zhu
3Department of Nuclear Medicine, Peking Union Medical College Hospital, Beijing, China
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Fan Wang
1Medical Isotopes Research Center, Peking University, Beijing, China
2Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China
6Interdisciplinary Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
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Journal of Nuclear Medicine: 55 (6)
Journal of Nuclear Medicine
Vol. 55, Issue 6
June 1, 2014
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Integrin αvβ6–Targeted SPECT Imaging for Pancreatic Cancer Detection
Zhaofei Liu, Hao Liu, Teng Ma, Xianlei Sun, Jiyun Shi, Bing Jia, Yi Sun, Jun Zhan, Hongquan Zhang, Zhaohui Zhu, Fan Wang
Journal of Nuclear Medicine Jun 2014, 55 (6) 989-994; DOI: 10.2967/jnumed.113.132969

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Integrin αvβ6–Targeted SPECT Imaging for Pancreatic Cancer Detection
Zhaofei Liu, Hao Liu, Teng Ma, Xianlei Sun, Jiyun Shi, Bing Jia, Yi Sun, Jun Zhan, Hongquan Zhang, Zhaohui Zhu, Fan Wang
Journal of Nuclear Medicine Jun 2014, 55 (6) 989-994; DOI: 10.2967/jnumed.113.132969
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Cited By...

  • SPECT/CT imaging, biodistribution and radiation dosimetry of a 177Lu-DOTA-integrin {alpha}v{beta}6 cystine knot peptide in a pancreatic cancer xenograft model
  • Clinical Translation of a 68Ga-Labeled Integrin {alpha}v{beta}6-Targeting Cyclic Radiotracer for PET Imaging of Pancreatic Cancer
  • Chemotherapy-Induced Macrophage Infiltration into Tumors Enhances Nanographene-Based Photodynamic Therapy
  • In Vivo PET Imaging of the Cancer Integrin {alpha}v{beta}6 Using 68Ga-Labeled Cyclic RGD Nonapeptides
  • Molecular Imaging of Post-Src Inhibition Tumor Signatures for Guiding Dasatinib Combination Therapy
  • The Effect of Bi-Terminal PEGylation of an Integrin {alpha}v{beta}6-Targeted 18F Peptide on Pharmacokinetics and Tumor Uptake
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More in this TOC Section

  • 11C-Methionine PET of Myocardial Inflammation in a Rat Model of Experimental Autoimmune Myocarditis
  • Counting Rate Characteristics and Image Distortion in Preclinical PET Imaging During Radiopharmaceutical Therapy
  • Design and Fabrication of Kidney Phantoms for Internal Radiation Dosimetry Using 3D Printing Technology
Show more Basic Science Investigations

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Keywords

  • pancreatic cancer
  • Molecular imaging
  • integrin αvβ6
  • phage display
  • SPECT/CT
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