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Journal of Nuclear Medicine

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About the Cover

January 1, 2014; Volume 55,Issue 1

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 8A;

SNMMI Newsline

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    Chalk River Resumes; Other Isotope Producers Announce Shutdowns
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 9N;
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    FDA Grants Orphan Drug Designation for 68Ga-DOTATOC
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 10N;
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    To the Newsline Editor
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 10N;
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    Drug Compounding Bill Signed into Law
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 11N;
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    FDA Issues Warning on Regadenoson and Adenosine
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 12N;
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    SNMMI Leadership Update: Strengthening Connections around the World
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 13N;
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    From the Literature
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 14N-16N;

Focus on Molecular Imaging

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    Imaging Cell Death
    André A. Neves and Kevin M. Brindle
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 1-4; DOI: https://doi.org/10.2967/jnumed.112.114264

Invited Perspectives

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    Whither Goest Thou, Radiopharmaceutical Therapy?
    Chaitanya Divgi
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 5-6; DOI: https://doi.org/10.2967/jnumed.113.127837
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    On the Destiny of (Copper) Species
    Jason L.J. Dearling and Alan B. Packard
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 7-8; DOI: https://doi.org/10.2967/jnumed.113.132480

Clinical Investigations

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    Radiopharmaceutical Therapy of Patients with Metastasized Melanoma with the Melanin-Binding Benzamide 131I-BA52
    Walter Mier, Clemens Kratochwil, Jessica C. Hassel, Frederik L. Giesel, Barbro Beijer, John W. Babich, Matthias Friebe, Michael Eisenhut, Alexander Enk and Uwe Haberkorn
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 9-14; DOI: https://doi.org/10.2967/jnumed.112.112789
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    123I-BZA2 as a Melanin-Targeted Radiotracer for the Identification of Melanoma Metastases: Results and Perspectives of a Multicenter Phase III Clinical Trial
    Florent Cachin, Elisabeth Miot-Noirault, Brigitte Gillet, Vanina Isnardi, Bruno Labeille, Pierre Payoux, Nicolas Meyer, Serge Cammilleri, Caroline Gaudy, Micheline Razzouk-Cadet, Jean Philippe Lacour, Florence Granel-Brocard, Christelle Tychyj, Fathalah Benbouzid, Jean Daniel Grange, Françoise Baulieu, Antony Kelly, Charles Merlin, Danielle Mestas, Françoise Gachon, Jean Michel Chezal, Françoise Degoul and Michel D’Incan
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 15-22; DOI: https://doi.org/10.2967/jnumed.113.123554
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    Functional Imaging of Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer Using 64Cu-DOTA-Trastuzumab PET
    Joanne E. Mortimer, James R. Bading, David M. Colcher, Peter S. Conti, Paul H. Frankel, Mary I. Carroll, Shan Tong, Erasmus Poku, Joshua K. Miles, John E. Shively and Andrew A. Raubitschek
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 23-29; DOI: https://doi.org/10.2967/jnumed.113.122630
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    18F-FDOPA PET for Differentiating Recurrent or Progressive Brain Metastatic Tumors from Late or Delayed Radiation Injury After Radiation Treatment
    Karlo J. Lizarraga, Martin Allen-Auerbach, Johannes Czernin, Antonio A.F. DeSalles, William H. Yong, Michael E. Phelps and Wei Chen
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 30-36; DOI: https://doi.org/10.2967/jnumed.113.121418
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    The Effect of Small Tumor Volumes on Studies of Intratumoral Heterogeneity of Tracer Uptake
    Frank J. Brooks and Perry W. Grigsby
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 37-42; DOI: https://doi.org/10.2967/jnumed.112.116715
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    Tumor Imaging in Patients with Advanced Tumors Using a New 99mTc-Radiolabeled Vitamin B12 Derivative
    Bert-Ram Sah, Roger Schibli, Robert Waibel, Lotta von Boehmer, Peter Bläuenstein, Ebba Nexo, Anass Johayem, Eliane Fischer, Ennio Müller, Jan D. Soyka, Alexander K. Knuth, Stefan K. Haerle, Pius August Schubiger, Niklaus G. Schaefer and Irene A. Burger
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 43-49; DOI: https://doi.org/10.2967/jnumed.113.122499
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    Additional Diagnostic Value of Integrated Analysis of Cardiac CTA and SPECT MPI Using the SMARTVis System in Patients with Suspected Coronary Artery Disease
    Hortense A. Kirişli, Vikas Gupta, Rahil Shahzad, Imad Al Younis, Anoeshka Dharampal, Robert-Jan van Geuns, Arthur J. Scholte, Michiel A. de Graaf, Raoul M.S. Joemai, Koen Nieman, Lucas van Vliet, Theo van Walsum, Boudewijn Lelieveldt and Wiro J. Niessen
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 50-57; DOI: https://doi.org/10.2967/jnumed.113.119842
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    Clinical Interpretation Standards and Quality Assurance for the Multicenter PET/CT Trial Rubidium-ARMI
    Jennifer M. Renaud, Ilias Mylonas, Brian McArdle, Taylor Dowsley, Kathy Yip, Eric Turcotte, Jean Guimond, Mikael Trottier, Philipe Pibarot, Conor Maguire, Lucille Lalonde, Karen Gulenchyn, Gerald Wisenberg, R. Glenn Wells, Terrence Ruddy, Benjamin Chow, Rob S.B. Beanlands and Robert A. deKemp
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 58-64; DOI: https://doi.org/10.2967/jnumed.112.117515
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    11C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists
    Koenraad J. Van Laere, Sandra M. Sanabria-Bohórquez, David P. Mozley, Donald H. Burns, Terence G. Hamill, Anne Van Hecken, Inge De Lepeleire, Michel Koole, Guy Bormans, Jan de Hoon, Marleen Depré, Kristine Cerchio, John Plalcza, Lingling Han, John Renger, Richard J. Hargreaves and Robert Iannone
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 65-72; DOI: https://doi.org/10.2967/jnumed.113.122515
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    In Vivo Detection of Monoaminergic Degeneration in Early Parkinson Disease by 18F-9-Fluoropropyl-(+)-Dihydrotetrabenzazine PET
    Shao-Cheng Lin, Kun-Ju Lin, Ing-Tsung Hsiao, Chia-Ju Hsieh, Wey-Yil Lin, Chin-Song Lu, Shiaw-Pyng Wey, Tzu-Chen Yen, Mei-Ping Kung and Yi-Hsin Weng
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 73-79; DOI: https://doi.org/10.2967/jnumed.113.121897
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    Cost Analysis of PET and Comprehensive Lifestyle Modification for the Reversal of Atherosclerosis
    Rigoberto I. Delgado, J. Michael Swint, David R. Lairson, Nils P. Johnson, K. Lance Gould and Stefano Sdringola
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 80-87; DOI: https://doi.org/10.2967/jnumed.113.119511
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    Qualitative and Quantitative Comparison of PET/CT and PET/MR Imaging in Clinical Practice
    Khalsa Z. Al-Nabhani, Rizwan Syed, Sofia Michopoulou, Jokha Alkalbani, Asim Afaq, Emmanouil Panagiotidis, Celia O’Meara, Ashley Groves, Peter Ell and Jamshed Bomanji
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 88-94; DOI: https://doi.org/10.2967/jnumed.113.123547
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    Clinical Cerenkov Luminescence Imaging of 18F-FDG
    Daniel L.J. Thorek, Christopher C. Riedl and Jan Grimm
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 95-98; DOI: https://doi.org/10.2967/jnumed.113.127266

Continuing Education

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    Advanced Imaging of Cardiac Sarcoidosis
    Imke Schatka and Frank M. Bengel
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 99-106; DOI: https://doi.org/10.2967/jnumed.112.115121

Basic Science Investigations

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    Anti–Prostate-Specific Membrane Antigen Liposomes Loaded with 225Ac for Potential Targeted Antivascular α-Particle Therapy of Cancer
    Amey Bandekar, Charles Zhu, Rohit Jindal, Frank Bruchertseifer, Alfred Morgenstern and Stavroula Sofou
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 107-114; DOI: https://doi.org/10.2967/jnumed.113.125476
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    Development of 111In-Labeled Liposomes for Vulnerable Atherosclerotic Plaque Imaging
    Mikako Ogawa, Izumi O. Umeda, Mutsumi Kosugi, Ayumi Kawai, Yuka Hamaya, Misato Takashima, Hongxia Yin, Takayuki Kudoh, Masaharu Seno and Yasuhiro Magata
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 115-120; DOI: https://doi.org/10.2967/jnumed.113.123158
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    “To Serve and Protect”: Enzyme Inhibitors as Radiopeptide Escorts Promote Tumor Targeting
    Berthold A. Nock, Theodosia Maina, Eric P. Krenning and Marion de Jong
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 121-127; DOI: https://doi.org/10.2967/jnumed.113.129411
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    A Comparison of the Behavior of 64Cu-Acetate and 64Cu-ATSM In Vitro and In Vivo
    Rebekka Hueting, Veerle Kersemans, Bart Cornelissen, Matthew Tredwell, Kamila Hussien, Martin Christlieb, Antony D. Gee, Jan Passchier, Sean C. Smart, Jonathan R. Dilworth, Véronique Gouverneur and Ruth J. Muschel
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 128-134; DOI: https://doi.org/10.2967/jnumed.113.119917
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    The Low Hepatic Toxicity per Gray of 90Y Glass Microspheres Is Linked to Their Transport in the Arterial Tree Favoring a Nonuniform Trapping as Observed in Posttherapy PET Imaging
    Stephan Walrand, Michel Hesse, Carlo Chiesa, Renaud Lhommel and Francois Jamar
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 135-140; DOI: https://doi.org/10.2967/jnumed.113.126839
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    11C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α1 Adrenoceptors in Brain
    Stal Saurav Shrestha, Jeih-San Liow, Shuiyu Lu, Kimberly Jenko, Robert L. Gladding, Per Svenningsson, Cheryl L. Morse, Sami S. Zoghbi, Victor W. Pike and Robert B. Innis
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 141-146; DOI: https://doi.org/10.2967/jnumed.113.125831
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    Evaluation of σ-1 Receptor Radioligand 18F-FTC-146 in Rats and Squirrel Monkeys Using PET
    Michelle L. James, Bin Shen, Carsten H. Nielsen, Deepak Behera, Christine L. Buckmaster, Christophe Mesangeau, Cristina Zavaleta, Pradeep K. Vuppala, Seshulatha Jamalapuram, Bonnie A. Avery, David M. Lyons, Christopher R. McCurdy, Sandip Biswal, Sanjiv S. Gambhir and Frederick T. Chin
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 147-153; DOI: https://doi.org/10.2967/jnumed.113.120261
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    18F-Alfatide II and 18F-FDG Dual-Tracer Dynamic PET for Parametric, Early Prediction of Tumor Response to Therapy
    Jinxia Guo, Ning Guo, Lixin Lang, Dale O. Kiesewetter, Qingguo Xie, Quanzheng Li, Henry S. Eden, Gang Niu and Xiaoyuan Chen
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 154-160; DOI: https://doi.org/10.2967/jnumed.113.122069
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    Implementation and Performance Evaluation of Simultaneous PET/MR Whole-Body Imaging with Continuous Table Motion
    Harald Braun, Susanne Ziegler, Markus G. Lentschig and Harald H. Quick
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 161-168; DOI: https://doi.org/10.2967/jnumed.113.123372
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    Improved Nuclear Medicine Uniformity Assessment with Noise Texture Analysis
    Jeffrey S. Nelson, Olav I. Christianson, Beth A. Harkness, Mark T. Madsen, Eugene Mah, Stephen R. Thomas, Habib Zaidi and Ehsan Samei
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 169-174; DOI: https://doi.org/10.2967/jnumed.113.125450

Book Review

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    Bone Tumors: A Practical Guide to Imaging
    Tamara Miner Haygood
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 175; DOI: https://doi.org/10.2967/jnumed.113.132449

Letters to the Editor

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    Discriminating Ability of 18F-FET PET for Several Cerebral Neoplastic Lesions
    Tomoyuki Kawada
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 176; DOI: https://doi.org/10.2967/jnumed.113.128231
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    Reply: Discriminating Ability of 18F-FET PET for Several Cerebral Neoplastic Lesions
    Karl-Josef Langen, Marion Rapp, Norbert Galldiks, Guido Reifenberger and Frank W. Floeth
    Journal of Nuclear Medicine January 1, 2014, 55 (1) 176; DOI: https://doi.org/10.2967/jnumed.113.134007
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In this issue

Journal of Nuclear Medicine: 55 (1)
Journal of Nuclear Medicine
Vol. 55, Issue 1
January 1, 2014
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • On the Destiny of (Copper) Species
  • Cost Analysis of PET and Comprehensive Lifestyle Modification for the Reversal of Atherosclerosis
  • Clinical Cerenkov Luminescence Imaging of 18F-FDG
  • Advanced Imaging of Cardiac Sarcoidosis
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  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
  • Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View
  • Slow but Evident Recovery from Neocortical Dysfunction and Cognitive Impairment in a Series of Chronic COVID-19 Patients
  • Tumor Response to Radiopharmaceutical Therapies: The Knowns and the Unknowns
  • Is FDG maximum standardized uptake value (SUV max) of primary breast cancer can predict axillary lymph node metastasis?
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