Article Figures & Data
Figures
- FIGURE 1.
Bar graph showing prevalence of normal or abnormal SPECT MPI findings across subgroups of CACS. y-axis denotes percentage of patients taken from entire study population of 326 patients.
- FIGURE 2.
Kaplan–Meier survival curves for cumulative survival free of MACE according to subgroups of normal or abnormal SPECT MPI findings and CACS above or below 1,314 (P < 0.05, log-rank test).
- FIGURE 3.
Cumulative MACE rate for patients with normal or abnormal SPECT MPI findings and CACS above or below cutoff value of 1,314 (P < 0.05, log-rank test).
Tables
Characteristic Value Mean age ± SD (y) 71.1 ± 8.5 Sex (n) Male 247 (76) Female 79 (24) Mean body mass index ± SD (kg/m2) 26 ± 6 Cardiovascular risk factors (n) Arterial hypertension 235 (72) Dyslipidaemia 218 (67) Current or former smoker 219 (67) Diabetes mellitus 68 (21) Positive family history 31 (10) Cardiovascular history (n) Known CAD 132 (41) Revascularization 97 (30) Myocardial infarction 62 (19) Stroke or transient ischemic attack 39 (12) Congestive heart failure 26 (8) Medication (n) Aspirin 201 (62) Angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker 181 (56) β-blocker 167 (51) Statin 178 (55) Nitroglycerin 14 (4) Data in parentheses are percentages.
Parameter No. of MACE patients (of 30 total) P Separate predictive values of SPECT MPI and CACS SPECT MPI 0.005 Normal findings (n = 242) 16 (7) Abnormal findings (n = 84) 14 (17) CACS 0.005 <1,314 (n = 216) 13 (6) ≥1,314 (n = 110) 17 (16) Added value of CACS combined with SPECT MPI Normal SPECT MPI findings 0.003 <1,314 (n = 173) 8 (5) ≥1,314 (n = 69) 8 (12) Abnormal SPECT MPI findings 0.002 <1,314 (n = 43) 5 (12) ≥1,314 (n = 41) 9 (22) P values indicate results from log-rank test. Data in parentheses are percentages.
Univariate Multivariate Characteristic HR 95% CI P HR 95% CI P Age 1.03 0.99–1.07 0.141 NA NS Sex 0.79 0.32–1.929 0.58 NA NS Surgical risk estimate 1.32 0.73–2.37 0.34 NA NS Lee index 1.73 1.20–2.46 0.003 1.55 1.06–2.26 0.022 SPECT MPI 2.61 1.28–5.36 0.009 NA NS CACS log 2.10 1.15–3.83 0.015 NA NS CACS ≥ 1,314 2.72 1.32–5.60 0.007 2.2 1.04–4.67 0.038 NA = not applicable; NS = not significant.
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