Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Meeting ReportCardiovascular: Clinical Science

Prevalence of ischemic heart disease (IHD) in asymptomatic patients with diabetes mellitus (DM) in developing countries

Raffaele Giubbini, Maurizio Dondi, Fernando Mut, Teresa Massardo, Lara Lusa and Ami Iskandrian
Journal of Nuclear Medicine May 2010, 51 (supplement 2) 1743;
Raffaele Giubbini
1Nuclear Medicine, University of Brescia, Brescia, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maurizio Dondi
2Division of Human Health, Nuclear Medicine Section, International Atomic Energy Agency, Vienna, Austria
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fernando Mut
3Servicio de Medicina Nuclear, Asociación Española, Montevideo, Uruguay
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Teresa Massardo
4Departamento Medicina, Seccion Medicina Nuclear, Hospital Clinico Universidad de Chile, Santiago, Chile
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lara Lusa
5Institute of Biomedical Informatics, University of Ljubljana, Ljubljana, Slovenia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ami Iskandrian
6Nuclear Cardiology, Division of CV Diseases, University of Alabama at Birmingham, Birmingham, AL
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

1743

Objectives The diagnostic values of exercise ECG and MPI in asymptomatic pts with type-2 DM are still debated. Little is known about prevalence of silent IHD in DM pts in developing countries. Aim of this IAEA coordinated clinical trial is the evaluation of IHD prevalence in DM pts and in controls (C) by MPI and exercise(EX) ECG.

Methods 468 pts (300 DM and 168 C) enrolled at 14 sites in Asia, Africa, and Latin America were analyzed. The inclusion criteria were: DM duration >5 yrs, age>40 yrs, near-normal baseline ECG, no history of CAD. The C group had to have ≥1 major risk factor(s) but no DM. All pts had EX testing with gated-SPECT MPI. ECGs and MPI were interpreted blindly in 2 core labs. The images were scored for SSS, SRS and SDS using a 17-segment model.

Results There were 61% men in DM and 54% in C (P=ns). Mean ages were 60.2 and 56.8(P<.001). Hypertension, hyperlipidemia, active smoking and family history of CAD were present in DM and C in 72% vs.67% (P=ns),58% vs.67%(P=ns)81% vs.71% (P=.03) and 31% vs.47% (P=.001) respectively. No differences were observed in DM and C in the use of statins, beta-blockers, ACEI and aspirin. By ECG, IHD was present in 15% of DM and 12% of C(P=NS). The SSS, SDS and SRS >3 was more in DM than C, 24% vs.13% (P=.007), 20% vs.11% (P=.018) and 6% vs.2% (P=.094). Rest LV ejection fraction was 66.5% in DM and 70.4% in C (P=.001). There were no differences in ischemia in the 3 continents: 26% in Africa, 19% in Asia and 19% in Latin America (P=ns).

Conclusions This first international study shows more ischemia by MPI than by ECG and more ischemia in DM than in C pts

Previous
Back to top

In this issue

Journal of Nuclear Medicine
Vol. 51, Issue supplement 2
May 2010
  • Table of Contents
  • Index by author
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Prevalence of ischemic heart disease (IHD) in asymptomatic patients with diabetes mellitus (DM) in developing countries
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Prevalence of ischemic heart disease (IHD) in asymptomatic patients with diabetes mellitus (DM) in developing countries
Raffaele Giubbini, Maurizio Dondi, Fernando Mut, Teresa Massardo, Lara Lusa, Ami Iskandrian
Journal of Nuclear Medicine May 2010, 51 (supplement 2) 1743;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Prevalence of ischemic heart disease (IHD) in asymptomatic patients with diabetes mellitus (DM) in developing countries
Raffaele Giubbini, Maurizio Dondi, Fernando Mut, Teresa Massardo, Lara Lusa, Ami Iskandrian
Journal of Nuclear Medicine May 2010, 51 (supplement 2) 1743;
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Info & Metrics

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

Cardiovascular: Clinical Science

  • Prognostic value of stress myocardial perfusion imaging in pre-kidney transplantation risk stratification
  • Is ultra-short ECG gated acquisition of C-11 acetate PET reliable for simultaneous MBF, oxidative metabolism and myocardial function assessment?
  • Electrophysiologic implications of PET-defined, active cardiac sarcoidosis
Show more Cardiovascular: Clinical Science

Cardiovascular-Clinical Posters

  • Repeatability of left ventricular dyssynchrony and function parameters in serial gated myocardial perfusion SPECT
  • The predictive value in pts with CAD using 99TcmN-NOET gated MPI
  • Body mass index is the only independent predictor of different degrees of carotid wall inflammation as revealed by FDG-PET/CT imaging in patients with known or suspected cardiovascular disease
Show more Cardiovascular-Clinical Posters

Similar Articles

SNMMI

© 2025 SNMMI

Powered by HighWire