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Research ArticleBrief Communication

The Value of 99mTc-Tetrofosmin Brain SPECT in Predicting Survival in Patients with Glioblastoma Multiforme

George A. Alexiou, Spyridon Tsiouris, Athanasios P. Kyritsis, George Fotakopoulos, Anna Goussia, Spyridon Voulgaris and Andreas D. Fotopoulos
Journal of Nuclear Medicine December 2010, 51 (12) 1923-1926; DOI: https://doi.org/10.2967/jnumed.110.080929
George A. Alexiou
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Spyridon Tsiouris
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Athanasios P. Kyritsis
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George Fotakopoulos
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Anna Goussia
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Spyridon Voulgaris
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Andreas D. Fotopoulos
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  • FIGURE 1.
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    FIGURE 1.

    Contrast-enhanced T1-weighted MR image (left) and 99mTc-tetrofosmin SPECT image (right) in one GBM patient exhibiting low tracer uptake (A) and in another with high uptake (B) (patients 6 and 18 from Table 1, respectively).

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    FIGURE 2.

    Graphs showing the relationship between 99mTc-tetrofosmin uptake (L/N cutoff, 4.7) and survival in GBM patients.

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    TABLE 1

    Detailed Patient Data

    Patient no.Age (y)SexLocationKPSResection99mTc-tetrofosmin uptakeSurvival (mo)
    160MR parietal100STR7.4311
    264ML temporal80STR2.515
    353ML temporal–parietal100STR9.611
    453MR temporal100NTR2.521
    566MR temporal90STR208
    654FR temporal100STR320
    761MR temporal100STR10.515
    858MR frontal80STR9.56
    978FR occipital100NTR4.111
    1061MR temporal90NTR5.4410
    1159FR occipital100NTR4.718
    1254FR temporal100NTR3.217
    1358ML temporal90NTR22.28
    1473MR parietal–occipital90STR11.39*
    1570MR frontal100STR15.910*
    1654FL frontal100NTR6.5710*
    1750MR temporal100STR106
    1869MR frontal–parietal80NTR165*
    • ↵* Alive.

    • STR = subtotal resection (75%–95%); NTR = near-total resection (>95%).

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Journal of Nuclear Medicine: 51 (12)
Journal of Nuclear Medicine
Vol. 51, Issue 12
December 1, 2010
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The Value of 99mTc-Tetrofosmin Brain SPECT in Predicting Survival in Patients with Glioblastoma Multiforme
George A. Alexiou, Spyridon Tsiouris, Athanasios P. Kyritsis, George Fotakopoulos, Anna Goussia, Spyridon Voulgaris, Andreas D. Fotopoulos
Journal of Nuclear Medicine Dec 2010, 51 (12) 1923-1926; DOI: 10.2967/jnumed.110.080929

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The Value of 99mTc-Tetrofosmin Brain SPECT in Predicting Survival in Patients with Glioblastoma Multiforme
George A. Alexiou, Spyridon Tsiouris, Athanasios P. Kyritsis, George Fotakopoulos, Anna Goussia, Spyridon Voulgaris, Andreas D. Fotopoulos
Journal of Nuclear Medicine Dec 2010, 51 (12) 1923-1926; DOI: 10.2967/jnumed.110.080929
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