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OtherBASIC SCIENCE INVESTIGATIONS

Tariquidar-Induced P-Glycoprotein Inhibition at the Rat Blood–Brain Barrier Studied with (R)-11C-Verapamil and PET

Jens P. Bankstahl, Claudia Kuntner, Aiman Abrahim, Rudolf Karch, Johann Stanek, Thomas Wanek, Wolfgang Wadsak, Kurt Kletter, Markus Müller, Wolfgang Löscher and Oliver Langer
Journal of Nuclear Medicine August 2008, 49 (8) 1328-1335; DOI: https://doi.org/10.2967/jnumed.108.051235
Jens P. Bankstahl
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Claudia Kuntner
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Aiman Abrahim
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Rudolf Karch
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Johann Stanek
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Thomas Wanek
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Wolfgang Wadsak
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Kurt Kletter
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Markus Müller
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Wolfgang Löscher
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Oliver Langer
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Article Information

vol. 49 no. 8 1328-1335
DOI 
https://doi.org/10.2967/jnumed.108.051235
PubMed 
18632828

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication January 29, 2008
  • Accepted for publication April 11, 2008
  • Published online July 30, 2008.

Article Versions

  • previous version (July 16, 2008 - 05:40).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2008 by Society of Nuclear Medicine

Author Information

  1. Jens P. Bankstahl * , 1 ,
  2. Claudia Kuntner * , 2 ,
  3. Aiman Abrahim 2 , 3 ,
  4. Rudolf Karch 4 ,
  5. Johann Stanek 2 ,
  6. Thomas Wanek 2 ,
  7. Wolfgang Wadsak 5 ,
  8. Kurt Kletter 5 ,
  9. Markus Müller 3 ,
  10. Wolfgang Löscher 1 and
  11. Oliver Langer 2 , 3
  1. 1Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany; 2Department of Radiopharmaceuticals and microPET Imaging, Austrian Research Centers GmbH–ARC, Seibersdorf, Austria; 3Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria; 4Department of Medical Computer Sciences, Medical University of Vienna, Vienna, Austria; and 5Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria
  1. For correspondence or reprints contact: Oliver Langer, Department of Radiopharmaceuticals and microPET Imaging, Austrian Research Centers GmbH–ARC, A-2444 Seibersdorf, Austria. E-mail: oliver.langer{at}arcs.ac.at
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  • Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[11C]verapamil PET
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Journal of Nuclear Medicine: 49 (8)
Journal of Nuclear Medicine
Vol. 49, Issue 8
August 2008
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Tariquidar-Induced P-Glycoprotein Inhibition at the Rat Blood–Brain Barrier Studied with (R)-11C-Verapamil and PET
Jens P. Bankstahl, Claudia Kuntner, Aiman Abrahim, Rudolf Karch, Johann Stanek, Thomas Wanek, Wolfgang Wadsak, Kurt Kletter, Markus Müller, Wolfgang Löscher, Oliver Langer
Journal of Nuclear Medicine Aug 2008, 49 (8) 1328-1335; DOI: 10.2967/jnumed.108.051235

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Tariquidar-Induced P-Glycoprotein Inhibition at the Rat Blood–Brain Barrier Studied with (R)-11C-Verapamil and PET
Jens P. Bankstahl, Claudia Kuntner, Aiman Abrahim, Rudolf Karch, Johann Stanek, Thomas Wanek, Wolfgang Wadsak, Kurt Kletter, Markus Müller, Wolfgang Löscher, Oliver Langer
Journal of Nuclear Medicine Aug 2008, 49 (8) 1328-1335; DOI: 10.2967/jnumed.108.051235
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