Article Figures & Data
Figures
- FIGURE 1.
18F-FDG PET images and SUVmax ratios of selected patients: patient from control group I with no history of atherosclerosis (A), patient from control group I with atherosclerosis of aorta and iliac arteries (confirmed by CT) (B), and GCA patients 3 (C) and 13 (D), both of whom had histologically proven GCA. On axial views, ROIs (black lines) were drawn over aortic arch (A–C) and ascending and descending parts of aorta (D). On coronal and sagittal views, arrows indicate 18F-FDG uptake into aortic vessel wall. Coronal view of B additionally shows uptake into iliac vessel wall.
- FIGURE 2.
(A) ROC analysis comparing GCA group with control group I: at cutoff of 1.0, sensitivity was 88.9% and specificity was 95.1%. (B) Cutoff optimization according to CLSI/NCCLS guidelines.
Tables
Patient no. Age (y) Sex Vessel-to- liver ratio Positive for ACR criteria Histology Duplex sonography Anemia Liver enzymes (GGT, AST, or ALT) Final diagnosis GCA true-positive patients 1 74 F 0.84 5 Pos. Pos. (scl.) Yes Elevated 2 61 M 0.93 4 ND Pos. (scl.) Yes Elevated 3 61 F 1.00 4 Pos. Pos. (ax.; br.) No Normal 4 57 F 1.03 4 ND Pos. (scl.; ax.; br.) Yes Normal 5 74 F 1.05 4 ND Pos. (scl.; ax.; br.) ND Elevated 6 64 F 1.09 3 ND ND Yes Elevated 7 67 F 1.09 3 ND Pos. (car.; scl.; ax.) Yes Normal 8 64 F 1.12 4 Pos. Pos. (scl.; ax.) Yes Elevated 9 62 F 1.14 5 Pos. Pos. (scl.; ax.) No Normal 10 62 F 1.15 4 ND Pos. (temp.) No Normal 11 74 F 1.18 5 Pos. Pos. (temp.) No Normal 12 64 F 1.19 5 Pos. Neg. No Elevated 13 56 F 1.24 4 Pos. Pos. (car.) Yes Normal 14 67 F 1.26 3 ND Neg. Yes Normal 15 65 F 1.33 5 Pos. Pos. (car.; scl.; ax.) Yes Elevated 16 65 M 1.43 3 ND ND Yes Normal 17 63 M 1.87 3 ND Pos. (ax.; br.) Yes Normal 18 57 F 1.88 3 ND Pos. (scl.) ND Normal GCA true-negative patients 19 60 F 0.79 3 ND Neg. Yes Elevated Rheumatoid arthritis 20 67 M 0.83 3 ND Neg. Yes Normal Paraneoplastic syndrome 21 76 F 0.84 3 ND Neg. Yes Elevated No diagnosis 22 59 F 0.85 3 ND Neg. No Normal No diagnosis 23 59 F 0.88 3 ND Neg. No Normal Polymyalgia rheumatica pos. = positive; neg. = negative; ND = not done; scl. = arteria subclavia; ax. = arteria axillaris; br. = arteria brachialis. car. = arteria carotis; temp. = arteria temporalis.
All patients had elevated erythrocyte sedimentation rate/C-reactive protein.
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