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Research ArticleCLINICAL INVESTIGATIONS

Novel Human IgG2b/Murine Chimeric Antitenascin Monoclonal Antibody Construct Radiolabeled with 131I and Administered into the Surgically Created Resection Cavity of Patients with Malignant Glioma: Phase I Trial Results

David A. Reardon, Jennifer A. Quinn, Gamal Akabani, R. Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, Roger E. McLendon, Charles N. Pegram, James M. Provenzale, Jeannette M. Dowell, Jeremy N. Rich, James J. Vredenburgh, Annick Desjardins, John H. Sampson, Sridharan Gururangan, Terence Z. Wong, Michael A. Badruddoja, Xiao-Guang Zhao, Darell D. Bigner and Michael R. Zalutsky
Journal of Nuclear Medicine June 2006, 47 (6) 912-918;
David A. Reardon
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Jennifer A. Quinn
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Gamal Akabani
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R. Edward Coleman
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Allan H. Friedman
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Henry S. Friedman
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James E. Herndon II
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Roger E. McLendon
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Charles N. Pegram
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James M. Provenzale
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Jeannette M. Dowell
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Jeremy N. Rich
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James J. Vredenburgh
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Annick Desjardins
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John H. Sampson
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Sridharan Gururangan
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Terence Z. Wong
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Michael A. Badruddoja
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Xiao-Guang Zhao
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Darell D. Bigner
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Michael R. Zalutsky
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Article Information

vol. 47 no. 6 912-918
PubMed 
16741299

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication December 6, 2005
  • Accepted for publication February 11, 2006
  • Published online June 1, 2006.

Copyright & Usage 
© 2006 by Society of Nuclear Medicine

Author Information

  1. David A. Reardon 1 , 2 ,
  2. Jennifer A. Quinn 3 ,
  3. Gamal Akabani 4 ,
  4. R. Edward Coleman 4 ,
  5. Allan H. Friedman 1 ,
  6. Henry S. Friedman 1 , 2 ,
  7. James E. Herndon II 5 ,
  8. Roger E. McLendon 6 ,
  9. Charles N. Pegram 6 ,
  10. James M. Provenzale 4 ,
  11. Jeannette M. Dowell 5 ,
  12. Jeremy N. Rich 3 ,
  13. James J. Vredenburgh 3 ,
  14. Annick Desjardins 3 ,
  15. John H. Sampson 1 ,
  16. Sridharan Gururangan 2 ,
  17. Terence Z. Wong 4 ,
  18. Michael A. Badruddoja 3 ,
  19. Xiao-Guang Zhao 6 ,
  20. Darell D. Bigner 6 and
  21. Michael R. Zalutsky 4
  1. 1Department of Surgery, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina; 2Department of Pediatrics, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina; 3Department of Medicine, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina; 4Department of Radiology, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina; 5Cancer Center Biostatistics, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina; and 6Department of Pathology, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina
  1. For correspondence or reprints contact: David A. Reardon, MD, Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Box 3624, Durham, NC 27710. E-mail: reard003{at}mc.duke.edu
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Journal of Nuclear Medicine: 47 (6)
Journal of Nuclear Medicine
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Novel Human IgG2b/Murine Chimeric Antitenascin Monoclonal Antibody Construct Radiolabeled with 131I and Administered into the Surgically Created Resection Cavity of Patients with Malignant Glioma: Phase I Trial Results
David A. Reardon, Jennifer A. Quinn, Gamal Akabani, R. Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, Roger E. McLendon, Charles N. Pegram, James M. Provenzale, Jeannette M. Dowell, Jeremy N. Rich, James J. Vredenburgh, Annick Desjardins, John H. Sampson, Sridharan Gururangan, Terence Z. Wong, Michael A. Badruddoja, Xiao-Guang Zhao, Darell D. Bigner, Michael R. Zalutsky
Journal of Nuclear Medicine Jun 2006, 47 (6) 912-918;

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Novel Human IgG2b/Murine Chimeric Antitenascin Monoclonal Antibody Construct Radiolabeled with 131I and Administered into the Surgically Created Resection Cavity of Patients with Malignant Glioma: Phase I Trial Results
David A. Reardon, Jennifer A. Quinn, Gamal Akabani, R. Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, Roger E. McLendon, Charles N. Pegram, James M. Provenzale, Jeannette M. Dowell, Jeremy N. Rich, James J. Vredenburgh, Annick Desjardins, John H. Sampson, Sridharan Gururangan, Terence Z. Wong, Michael A. Badruddoja, Xiao-Guang Zhao, Darell D. Bigner, Michael R. Zalutsky
Journal of Nuclear Medicine Jun 2006, 47 (6) 912-918;
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