Article Figures & Data
Figures
- FIGURE 1.
Kaplan–Meier survival curve for cardiac death, nonfatal MI, and revascularization.
Tables
Characteristic Ischemic ECG (n = 72) Nonischemic ECG (n = 557) P value Age (y) 61 ± 11 59 ± 11 NS Female 60 (83) 391 (70) <0.03 BMI (kg/m2) 27 ± 5 29 ± 7 NS Cardiac risk factors Smoker 7 (10) 89 (16) NS Hypertension 44 (61) 276 (50) NS Diabetes 14 (20) 71 (13) NS Dyslipidemia 42 (58) 307 (55) NS Family history of CAD 35 (49) 265 (48) NS Cardiac medications Aspirin 37 (52) 247 (44) NS β-Blocker 25 (35) 179 (32) NS HMG-CoA reductase 34 (49) 212 (38) NS ACE-I 21 (30) 132 (24) NS Past medical history MI 7 (10) 52 (9) NS PCI 6 (8) 70 (13) NS CABG 2 (3) 18 (3) NS Coronary angiography 25 (35) 134 (24) NS NS = not significant; BMI = body mass index; HMG-CoA reductase = statin; ACE-I = angiotensin-converting enzyme inhibitor.
Values in parentheses are percentages.
- TABLE 2
Rest and Dipyridamole Stress 82Rb PET in Patients With and Without Ischemic ECG Changes
Parameter Ischemic ECG (n = 72) Nonischemic ECG (n = 557) P value Resting heart rate (bpm) 73 ± 13 66 ± 11 <0.001 Resting blood pressure (mm Hg) Systolic 147 ± 20 140 ± 22 0.01 Diastolic 79 ± 11 76 ± 13 0.01 Peak stress heart rate (bpm) 99 ± 16 85 ± 14 <0.001 Peak stress blood pressure (mm Hg) Systolic 150 ± 24 138 ± 22 <0.001 Diastolic 78 ± 20 73 ± 14 NS Rate · pressure product Rest 10,717 ± 2,545 9,278 ± 2,246 <0.001 Stress 14,916 ± 3,564 11,722 ± 2,774 <0.001 Persantine-induced chest pain* 39 (54) 230 (41) <0.05 Stress ECG ST depression* 72 (100) 0 <0.001 Leads with ST depression 3.6 ± 1.9 0 <0.001 Maximum ST depression (mm) 1.3 ± 0.4 0 <0.001 MPI SSS 0.15 ± 0.53 0.19 ± 0.49 NS SRS 0.32 ± 0.73 0.7 ± 1.58 <0.03 SDS 0.10 ± 0.31 0.07 ± 0.23 NS ↵* Values in parentheses are percentages.
bpm = beats per minute; NS = not significant.
Parameter Ischemic ECG (n = 72) Nonischemic ECG (n = 557) P value Mean follow-up (mo) 26.3 ± 11.0 27.2 ± 13.3 NS Cardiac death 0 0 NS Nonfatal MI 1 (1.4) 0 NS Revascularization 2 (2.8) 11 (2.0) NS PCI 1 (1.4) 8 (1.4) NS CABG 1 (1.4) 3 (0.5) NS Coronary angiography 3 (4.2) 22 (4.0) NS Cardiac death and nonfatal MI 1 (1.4) 0 NS Cardiac death, nonfatal MI, or revascularization 3 (4.2) 11 (2.0) NS NS = not significant.
Values in parentheses are percentages.
Vasodilator-induced ST depression Chow et al. (this study) PET (n = 72) Klodas et al. (9) SPECT (n = 49) Abbott et al. (10) SPECT (n = 66) Age (y) 61 ± 11.0 67 ± 10 64.8 ± 15.3 Female (%) 83 88 82 β-Blocker (%) 35 24 CAD (%) 30 30 MI (%) 10 2.0 Revascularization (%) 9.7 10.2 Dyslipidemia (%) 58 55 42 Hypertension (%) 61 57 77 Diabetes (%) 20 14 32 Smoker (%) 10 33 29 - TABLE 6
Patient Demographics: Patients Lost to Follow-Up or Refused to Participate in Study
Characteristic Patients with follow-up (n = 629) Patients without follow-up (n = 65) P value Age (y) 59 ± 11 56 ± 12 <0.03 Female 451 (72) 38 (58) <0.05 BMI (kg/m2) 29 ± 7 29 ± 7 NS Cardiac risk factors Smoker 96 (15) 8 (12) NS Hypertension 320 (51) 27 (42) NS Diabetes 85 (14) 12 (18) NS Dyslipidemia 349 (56) 25 (38) <0.03 Family history of CAD 300 (48) 27 (42) NS Cardiac medications Aspirin 284 (45) 27 (42) NS β-Blocker 204 (33) 20 (31) NS HMG-CoA reductase 247 (39) 18 (28) NS ACE-I 153 (24) 9 (14) NS Past medical history MI 59 (9) 8 (12) NS PCI 76 (12) 5 (8) NS CABG 20 (3) 1 (2) NS Coronary angiography 159 (25) 16 (25) NS BMI = body mass index; NS = not significant; HMG-CoA reductase = statin; ACE-I = angiotensin-converting enzyme inhibitor.
Values in parentheses are percentages.
Parameter Patients with follow-up (n = 629) Patients without follow-up (n = 65) P value Resting heart rate (bpm) 67 ± 12 68 ± 12 NS Resting blood pressure (mm Hg) Systolic 141 ± 22 144 ± 24 NS Diastolic 76 ± 13 78 ± 12 NS Peak stress heart rate (bpm) 86 ± 15 85 ± 15 NS Peak stress blood pressure (mm Hg) Systolic 140 ± 23 141 ± 24 NS Diastolic 73 ± 15 74 ± 12 NS Rate · pressure product Rest 9,443 ± 2,325 9,749 ± 2,219 NS Stress 12,087 ± 3,047 11,926 ± 2,688 NS Dipyridamole-induced chest pain* 269 (43) 23 (35) NS MPI SSS 0.19 ± 0.49 0.22 ± 0.46 NS SRS 0.65 ± 1.50 0.72 ± 1.20 NS SDS 0.08 ± 0.24 0.05 ± 0.19 NS ↵* Values in parentheses are percentages.
bpm = beats per minute; NS = not significant.
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