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OtherClinical Investigations

The Role of Gastric Distention in Differentiating Recurrent Tumor from Physiologic Uptake in the Remnant Stomach on 18F-FDG PET

Mijin Yun, Hyun Seok Choi, Eunhye Yoo, Jung Kyun Bong, Young Hoon Ryu and Jong Doo Lee
Journal of Nuclear Medicine June 2005, 46 (6) 953-957;
Mijin Yun
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Hyun Seok Choi
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Eunhye Yoo
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Jung Kyun Bong
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Young Hoon Ryu
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Jong Doo Lee
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  • FIGURE 1.
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    FIGURE 1.

    Axial (left), coronal (middle), and sagittal (right) 18F-FDG PET images of patient with physiologic 18F-FDG uptake in remnant stomach. (A–C) Before water ingestion, increased 18F-FDG uptake is seen in remnant stomach. (D–F) After water ingestion, uptake disappears.

  • FIGURE 2.
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    FIGURE 2.

    Axial (left), coronal (middle), and sagittal (right) 18F-FDG PET images of patient with recurrent tumor in remnant stomach. (A–C) Before water ingestion, round area of increased 18F-FDG uptake is seen in remnant stomach. (D–F) After water ingestion, uptake persists.

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    FIGURE 3.

    Axial whole-body PET images of patient with recurrent signet ring adenocarcinoma in remnant stomach. (A) On these consecutive images obtained before water ingestion, peculiar area of increased 18F-FDG uptake is seen in remnant stomach (interpreted as true positive). (B) On these consecutive images obtained after water ingestion, decrease in 18F-FDG uptake produces false-negative result. In this case, initial 18F-FDG uptake might have been physiologic rather than due to recurrent tumor, considering tumor histology and result on spot images.

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    TABLE 1

    Primary Tumors

    CharacteristicNo. of patients
    Histology
        Adenocarcinoma, well differentiated2
        Adenocarcinoma, moderately differentiated6
        Adenocarcinoma, poorly differentiated18
        Adenocarcinoma, mucinous1
        Signet ring cell carcinoma3
    Stage
        I7
        II4
        III15
        IV4
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    TABLE 2

    Diagnostic Performance of Visual and SUV Analysis in Patients With or Without Recurrence in Remnant Stomach

    Type of analysisTrue-positiveFalse-negativeTrue-negativeFalse-positive
    Visual
        Whole body16194
        Spot152121
    SUV
        First criterion170211
        Adding second criterion134130
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Journal of Nuclear Medicine: 46 (6)
Journal of Nuclear Medicine
Vol. 46, Issue 6
June 1, 2005
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The Role of Gastric Distention in Differentiating Recurrent Tumor from Physiologic Uptake in the Remnant Stomach on 18F-FDG PET
Mijin Yun, Hyun Seok Choi, Eunhye Yoo, Jung Kyun Bong, Young Hoon Ryu, Jong Doo Lee
Journal of Nuclear Medicine Jun 2005, 46 (6) 953-957;

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The Role of Gastric Distention in Differentiating Recurrent Tumor from Physiologic Uptake in the Remnant Stomach on 18F-FDG PET
Mijin Yun, Hyun Seok Choi, Eunhye Yoo, Jung Kyun Bong, Young Hoon Ryu, Jong Doo Lee
Journal of Nuclear Medicine Jun 2005, 46 (6) 953-957;
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