Article Figures & Data
Figures
- FIGURE 1.
Examples of PET images on 2 different levels show parallel decrease of FMZ-BP, CBF, CMRo2, and an increase of OEF in patient with right ICA occlusion who showed internal borderzone infarction (red arrow) with cortical extension (green arrow) on corresponding MR images. In addition to markedly reduced FMZ-BP in region with small cortical infarcts, a decrease of FMZ-BP was found in normal-appearing cerebral cortex beyond borderzone infarcts. Mean hemispheric values of ipsilateral/contralateral hemisphere: FMZ-BP ratio, 1.00/1.16; CBF, 20.4/26.1 mL/100 g/min; CMRo2, 2.37/2.87 mL/100 g/min; OEF, 61.9%/58.3%.
- FIGURE 2.
Examples of PET images show distribution of decrease of FMZ-BP in patient with right ICA occlusion (patient in Fig. 1). Although decreases of FMZ-BP predominated in frontoparietal region near borderzone infarction, an extensive decrease of FMZ-BP was found in MCA distribution.
- FIGURE 3.
Scatter diagrams plot CBF (A), CMRo2 (B), and OEF (C) against cerebral/cerebellar FMZ-BP ratio in 62 hemispheres with carotid artery disease. The lines were generated by simple linear regression. Ext = solitary external borderzone infarct; Int = solitary internal borderzone infarct; Both = both borderzone infarct; None = no borderzone infarct.
Tables
Characteristic Asymptomatic TIA Stroke No. of patients 21 12 29 ICA occlusion/stenosis 8/13 5/7 16/13 Asymptomatic contralateral carotid stenosis >50% (n) 2 2 6 Asymptomatic vertebral artery stenosis >50% (n) 4 2 1 Type of lesion (n) External borderzone infarcts 0 0 12 Territorial infarcts 1 0 10 Internal borderzone infarcts 0 1 12 Other white matter infarcts 4 4 7 Striatocapsular infarcts 0 0 5 Lacunar infarcts 8 2 12 TIA = transient ischemic attack.
- TABLE 2
Ischemic Lesions and Cerebral/Cerebellar FMZ BP Ratio in Hemisphere with Carotid Artery Disease
Type of lesion Yes No External borderzone infarcts (n = 12) 1.02 ± 0.07* 1.31 ± 0.16 Territorial infarcts (n = 11) 1.22 ± 0.12 1.26 ± 0.20 Internal borderzone infarcts (n = 13) 1.13 ± 0.14* 1.29 ± 0.19 Other white matter infarcts (n = 15) 1.29 ± 0.17 1.24 ± 0.19 Striatocapsular infarcts (n = 5) 1.20 ± 0.16 1.26 ± 0.19 Lacunar infarcts (n = 22) 1.22 ± 0.17 1.27 ± 0.20 ↵* P < 0.008 (0.05/6) vs. corresponding value in No group (Student t test).
- TABLE 3
Multiple Linear Regression Analysis with Cerebral/Cerebellar FMZ BP Ratio in Hemisphere with Carotid Artery Disease as Dependent Variable
Parameter Coefficient SE t P value External borderzone infarcts (no = 0, yes = 1) −0.285 0.056 −5.11 <0.0001 Age (y) −0.003 0.003 −1.06 0.292 Territorial infarcts (no = 0, yes = 1) −0.076 0.053 −1.43 0.157 Internal borderzone infarcts (no = 0, yes = 1) −0.058 0.054 −1.06 0.293 Other white matter infarcts (no = 0, yes = 1) 0.011 0.046 0.24 0.809 Striatocapsular infarcts (no = 0, yes = 1) −0.137 0.072 −1.90 0.062 Lacunar infarcts (no = 0, yes = 1) −0.045 0.043 −1.04 0.299
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