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Journal of Nuclear Medicine

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OtherClinical Investigations

Toward Clinical Application of Neuropsychological Activation Probes with SPECT: A Spatial Working Memory Task

Ingeborg Goethals, Kurt Audenaert, Filip Jacobs, Christophe Van De Wiele, Griet Vermeir, André Vandierendonck, Cees Van Heeringen and Rudi Dierckx
Journal of Nuclear Medicine November 2002, 43 (11) 1426-1431;
Ingeborg Goethals
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Kurt Audenaert
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Filip Jacobs
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Christophe Van De Wiele
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Griet Vermeir
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André Vandierendonck
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Cees Van Heeringen
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Rudi Dierckx
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  • FIGURE 1.
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    FIGURE 1.

    Computer screen with target rectangles (stimuli). Solid lines indicate bright-white and dotted lines indicate gray-shaded rectangles on computer screen.

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    FIGURE 2.

    Split-dose activation paradigm.

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    FIGURE 3.

    Glass-brain images indicate projections of activation clusters in the memory task.

Tables

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    TABLE 1

    Mean Behavioral Responses in Perception and Memory Tasks

    ParameterPerception taskMemory task
    L handR handL handR hand
    Reaction time (ms)331344465459
    Accuracy (% error rate)0.40.64.65.4
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    TABLE 2

    SPM: Cluster-Level P Values and Activated Brain Regions During Memory Task

    Cluster-level Pcorrected valueTalairach coordinatesRegion
    xyz
    0.011−45−3657L lobulus parietalis inferior (BA 40)
    0.027362748R gyrus frontalis superior (BA 8)
    0.003243336R gyrus frontalis medius (BA 9)
    0.01212669R gyrus frontalis superior (BA 6)
    0.00048−4233L lobulus parietalis inferior (BA 40)
    0.0024242−12R gyrus frontalis inferior (BA 47)
    • BA = Brodmann area.

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Journal of Nuclear Medicine
Vol. 43, Issue 11
November 1, 2002
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Toward Clinical Application of Neuropsychological Activation Probes with SPECT: A Spatial Working Memory Task
Ingeborg Goethals, Kurt Audenaert, Filip Jacobs, Christophe Van De Wiele, Griet Vermeir, André Vandierendonck, Cees Van Heeringen, Rudi Dierckx
Journal of Nuclear Medicine Nov 2002, 43 (11) 1426-1431;

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Toward Clinical Application of Neuropsychological Activation Probes with SPECT: A Spatial Working Memory Task
Ingeborg Goethals, Kurt Audenaert, Filip Jacobs, Christophe Van De Wiele, Griet Vermeir, André Vandierendonck, Cees Van Heeringen, Rudi Dierckx
Journal of Nuclear Medicine Nov 2002, 43 (11) 1426-1431;
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