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Journal of Nuclear Medicine

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OtherCLINICAL INVESTIGATIONS

Paclitaxel-Based Chemotherapy for Non–Small Cell Lung Cancer: Predicting the Response with 99mTc-Tetrofosmin Chest Imaging

Chia-Hung Kao, Jih-Fang Hsieh, Shih-Chuan Tsai, Yung-Jen Ho, Sheng-Ping ChangLai and Jong-Kang Lee
Journal of Nuclear Medicine January 2001, 42 (1) 17-20;
Chia-Hung Kao
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Jih-Fang Hsieh
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Shih-Chuan Tsai
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Yung-Jen Ho
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Sheng-Ping ChangLai
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Jong-Kang Lee
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  • FIGURE 1.
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    FIGURE 1.

    In patient 1, who had good response to paclitaxel, both early and delayed anterior and posterior 99mTc-TF chest images show significant 99mTc-TF uptake by lung cancer (arrows).

  • FIGURE 2.
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    FIGURE 2.

    In patient 11, who had poor response to paclitaxel, both early and delayed anterior and posterior 99mTc-TF chest images show no definite 99mTc-TF uptake by lung cancer.

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    TABLE 1.

    Patient Data

    Patient no.SexAge (y)Tumor size (cm)StageCell types99mTc-TF chest imagesChemotherapeutic response
    Early T/NLDelayed T/NLRI (%)
    1F468 × 6IVSCC1.601.40−12.50Good
    2M475 × 6IIIbAdenocarcinoma1.801.70−5.56Good
    3M524 × 2IVAdenocarcinoma1.401.30−7.14Good
    4F576 × 4.5IIIbSCC1.901.80−5.26Good
    5M595 × 4.5IVSCC1.301.300.00Good
    6F605 × 4IIIbSCC1.301.20−7.69Good
    7F625 × 3IVAdenocarcinoma1.501.40−6.67Good
    8M635 × 6IVAdenocarcinoma2.001.90−5.00Good
    9M668 × 6IIIbAdenocarcinoma1.701.700.00Good
    10M674 × 4IVAdenocarcinoma1.401.30−7.14Good
    11F432.5 × 4IVAdenocarcinoma1.001.000.00Poor
    12M453 × 5IVSCC1.201.10−8.33Poor
    13F484.5 × 5IVAdenocarcinoma1.001.000.00Poor
    14F543 × 3IVSCC1.201.10−8.33Poor
    15M587 × 5IVAdenocarcinoma1.101.00−9.09Poor
    16M619 × 7IVAdenocarcinoma1.101.00−9.09Poor
    17M653.5 × 3IVAdenocarcinoma1.201.10−8.33Poor
    18M653.5 × 3IVAdenocarcinoma1.001.000.00Poor
    19M693 × 3IIIbSCC1.001.000.00Poor
    20M706 × 6IIIbSCC1.101.00−9.09Poor
    • SCC = squamous cell carcinoma.

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Journal of Nuclear Medicine
Vol. 42, Issue 1
January 1, 2001
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Paclitaxel-Based Chemotherapy for Non–Small Cell Lung Cancer: Predicting the Response with 99mTc-Tetrofosmin Chest Imaging
Chia-Hung Kao, Jih-Fang Hsieh, Shih-Chuan Tsai, Yung-Jen Ho, Sheng-Ping ChangLai, Jong-Kang Lee
Journal of Nuclear Medicine Jan 2001, 42 (1) 17-20;

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Paclitaxel-Based Chemotherapy for Non–Small Cell Lung Cancer: Predicting the Response with 99mTc-Tetrofosmin Chest Imaging
Chia-Hung Kao, Jih-Fang Hsieh, Shih-Chuan Tsai, Yung-Jen Ho, Sheng-Ping ChangLai, Jong-Kang Lee
Journal of Nuclear Medicine Jan 2001, 42 (1) 17-20;
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