Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Meeting ReportPhysics, Instrumentation & Data Sciences - Data Analysis & Management

The value of 18F-FDG PET/MR radiomic features in predicting the malignant degree of pancreatic intraductal papillary mucinous tumors(IPMN)

Yuanfan Xu
Journal of Nuclear Medicine June 2024, 65 (supplement 2) 242587;
Yuanfan Xu
1HangZhou Universal Medical Imaging Diagnostic Center
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

242587

Introduction: The malignancy degree of pancreatic IPMN determines its surgical methods and whether to continue other treatments after surgery.The purpose of this study is to explore the value of 18F-FDG PET/MR radiomics features in predicting malignant degree of pancreatic IPMN,thereby providing guidance for clinical treatment.

Methods: The clinical and PET/MR imaging data of 189 patients with IPMN were collected, including 76 cases of Benign, 55 cases of borderline and 58 cases of malignant. Pathological and clinical diagnosis results serve as the gold standard for diagnosis. We used AK software to extract the most relevant imageomics features for tumor classification, and randomly divided the two groups of images into training set (70%) and test set (30%). The maximum correlation and minimum redundancy (mRMR) and minimum absolute shrinkage and selection operator (LASSO) methods were used to select features from 1800 features extracted from MR and PET, and finally 9 best features were retained. Multivariate logistic regression analysis was performed using the radiomics features and clinical variables to establish the prediction model. The receiver operating characteristic (ROC) analysis is used to evaluate the prediction model.

Results: The established PET/MR imaging features have good prediction efficiency for distinguishing malignant degree of pancreatic IPMN(P<0.05). The AUC of the training group and the validation group were 0.945 (95% CI: 0.787-0.956), 0.934 (95% CI: 0.776 – 0.945).The calibration curve showed that the nomogram of radiomics had goodness of fit, and DCA proved that the nomogram of radiomics was useful in clinical practice.

Conclusions: The prediction model of PET/MR radiomics features can be used as an auxiliary method to predict the malignant degree of pancreatic IPMN. It can also provide objective basis for clinical diagnosis and individualized treatment, and may has guiding significance for clinical treatment.

Previous
Back to top

In this issue

Journal of Nuclear Medicine
Vol. 65, Issue supplement 2
June 1, 2024
  • Table of Contents
  • Index by author
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The value of 18F-FDG PET/MR radiomic features in predicting the malignant degree of pancreatic intraductal papillary mucinous tumors(IPMN)
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
The value of 18F-FDG PET/MR radiomic features in predicting the malignant degree of pancreatic intraductal papillary mucinous tumors(IPMN)
Yuanfan Xu
Journal of Nuclear Medicine Jun 2024, 65 (supplement 2) 242587;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The value of 18F-FDG PET/MR radiomic features in predicting the malignant degree of pancreatic intraductal papillary mucinous tumors(IPMN)
Yuanfan Xu
Journal of Nuclear Medicine Jun 2024, 65 (supplement 2) 242587;
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Info & Metrics

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Validation of the lesion quantification of a learning-based PET image filter
  • Advanced Delay Correction Using TAC Integration and Newton-Raphson Method in Dynamic PET Imaging
Show more Physics, Instrumentation & Data Sciences - Data Analysis & Management

Similar Articles

SNMMI

© 2025 SNMMI

Powered by HighWire