Abstract
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Introduction: To explore the value and advantages of PET/MRI in the diagnosis of malignant melanoma N staging and M staging.
Methods: The clinical and imaging data of 41 patients with malignant melanoma were retrospectively analyzed, AJCC stage II-IV, according to histopathological examination or follow-up confirmation as the gold standard, there were 28 cases of lymph node metastasis (N stage) and 18 cases of distant metastasis (M stage). The diagnostic results of PET/MR and MR in N staging and M staging of malignant melanoma patients were analyzed. The Kappa consistency test and paired χ2 test were used to evaluate the diagnostic consistency and difference between PET/MRI, MRI and the gold standard, respectively.
Results: 41 cases of melanoma, a total of 230 lesions were found, 225 lesions were detected by PET/MR, and 210 lesions were detected by MRI. The detection rate of PET/MR (97.8%) was higher than that of MRI (91.3%), but the difference was not statistically significant significance (P>0.05). PET/MRI and MRI had higher coincidence rates in the diagnosis of melanoma N stage, 100% (28/28) and 89.3% (25/28), respectively, with no significant difference (P>0.05). The diagnostic coincidence rates for M staging were 94.4% (17/18) and 61.1% (11/18), and the difference was statistically significant (P<0.05).Compared with the gold standard, the diagnostic consistency of PET/MR staging is better (Kap-pa=0.857); the diagnostic consistency of MRI staging is general (Kap-pa=0.532); the two methods have statistical differences in the diagnosis of melanoma staging study meaning (P<0.05).
Conclusions: PET/MR can provide more accurate tumor staging for malignant melanoma, especially in M staging.
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