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Research ArticleClinical Investigation

Pitfalls and Common Findings in 68Ga-FAPI PET: A Pictorial Analysis

Lukas Kessler, Justin Ferdinandus, Nader Hirmas, Fadi Zarrad, Michael Nader, David Kersting, Manuel Weber, Sandra Kazek, Miriam Sraieb, Rainer Hamacher, Katharina Lueckerath, Lale Umutlu, Wolfgang P. Fendler and Christoph Rischpler
Journal of Nuclear Medicine June 2022, 63 (6) 890-896; DOI: https://doi.org/10.2967/jnumed.121.262808
Lukas Kessler
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Justin Ferdinandus
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Nader Hirmas
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Fadi Zarrad
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Michael Nader
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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David Kersting
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Manuel Weber
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Sandra Kazek
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Miriam Sraieb
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Rainer Hamacher
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
3Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany; and
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Katharina Lueckerath
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Lale Umutlu
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
4Institute of Diagnostic and Interventional Radiology, University Hospital Essen, University of Duisburg–Essen, Essen, Germany
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Wolfgang P. Fendler
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Christoph Rischpler
1Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
2German Cancer Consortium, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Journal of Nuclear Medicine: 63 (6)
Journal of Nuclear Medicine
Vol. 63, Issue 6
June 1, 2022
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Pitfalls and Common Findings in 68Ga-FAPI PET: A Pictorial Analysis
Lukas Kessler, Justin Ferdinandus, Nader Hirmas, Fadi Zarrad, Michael Nader, David Kersting, Manuel Weber, Sandra Kazek, Miriam Sraieb, Rainer Hamacher, Katharina Lueckerath, Lale Umutlu, Wolfgang P. Fendler, Christoph Rischpler
Journal of Nuclear Medicine Jun 2022, 63 (6) 890-896; DOI: 10.2967/jnumed.121.262808

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Pitfalls and Common Findings in 68Ga-FAPI PET: A Pictorial Analysis
Lukas Kessler, Justin Ferdinandus, Nader Hirmas, Fadi Zarrad, Michael Nader, David Kersting, Manuel Weber, Sandra Kazek, Miriam Sraieb, Rainer Hamacher, Katharina Lueckerath, Lale Umutlu, Wolfgang P. Fendler, Christoph Rischpler
Journal of Nuclear Medicine Jun 2022, 63 (6) 890-896; DOI: 10.2967/jnumed.121.262808
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Cited By...

  • SNMMI Procedure Standard/EANM Practice Guideline for Fibroblast Activation Protein (FAP) PET
  • Prognostic Implications of 68Ga-FAPI-46 PET/CT-Derived Parameters on Overall Survival in Various Types of Solid Tumors
  • Diagnostic Accuracy of 68Ga-FAPI Versus 18F-FDG PET in Patients with Various Malignancies
  • Tumor Characterization by [68Ga]FAPI-46 PET/CT Can Improve Treatment Selection for Pancreatic Cancer Patients: An Interim Analysis of a Prospective Clinical Trial
  • Initial Evaluation of [18F]FAPI-74 PET for Various Histopathologically Confirmed Cancers and Benign Lesions
  • Initial Evaluation of [18F]FAPI-74 PET for Various Histopathologically Confirmed Cancers and Benign Lesions
  • Fibroblast Activation Protein Inhibitor-Based Radionuclide Therapies: Current Status and Future Directions
  • 68Ga-FAPI PET/CT Interobserver Agreement on Tumor Assessment: An International Multicenter Prospective Study
  • Fibroblast-Activation Protein PET and Histopathology in a Single-Center Database of 324 Patients and 21 Tumor Entities
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More in this TOC Section

  • First-in-Human Study of 18F-Labeled PET Tracer for Glutamate AMPA Receptor [18F]K-40: A Derivative of [11C]K-2
  • Detection of HER2-Low Lesions Using HER2-Targeted PET Imaging in Patients with Metastatic Breast Cancer: A Paired HER2 PET and Tumor Biopsy Analysis
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Keywords

  • cancer imaging
  • FAPI
  • fibroblast activation protein
  • PET
  • pitfalls
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