Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Research ArticleContinuing Education

Prostate Cancer Treatment: 177Lu-PSMA-617 Considerations, Concepts, and Limitations

Oliver Sartor and Ken Herrmann
Journal of Nuclear Medicine June 2022, 63 (6) 823-829; DOI: https://doi.org/10.2967/jnumed.121.262413
Oliver Sartor
1Tulane University School of Medicine, Tulane Cancer Center, New Orleans, Louisiana; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ken Herrmann
2University of Duisburg–Essen and German Cancer Consortium, University Hospital Essen, Essen, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Article Information

vol. 63 no. 6 823-829
DOI 
https://doi.org/10.2967/jnumed.121.262413
PubMed 
35649665

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication January 13, 2022
  • Revision received April 7, 2022
  • Published online June 1, 2022.

Copyright & Usage 
© 2022 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Oliver Sartor1 and
  2. Ken Herrmann2
  1. 1Tulane University School of Medicine, Tulane Cancer Center, New Orleans, Louisiana; and
  2. 2University of Duisburg–Essen and German Cancer Consortium, University Hospital Essen, Essen, Germany
  3. Learning Objectives: On successful completion of this activity, participants should be able to describe (1) selection criteria employed in the VISION trial; (2) the VISION trial in the context of other therapies for advanced prostate cancer; and (3) an overview of newer phase III protocols using radiopharmaceuticals in the treatment of advanced prostate cancer.Financial Disclosure: Dr. Sartor is a consultant/advisor for Advanced Accelerator Applications (AAA), Amgen, Astellas, AstraZeneca, Bayer, Blue Earth Diagnostics, Inc., Bavarian Nordic, Bristol Myers Squibb, Clarity Pharmaceuticals, Clovis, Constellation, Curium, Dendreon, EMD Serono, Fusion, Isotopen Technologien Meunchen, Janssen, JNJ, Myovant, Myriad, Noria Therapeutics, Inc., Novartis, Noxopharm, Nucligen, Progenics, POINT Biopharma, Pfizer, Sanofi, Tenebio, Telix, and Theragnostics; has investment interest in Clarity, Lantheus, Noria, Ratio, Nucligen, and Telix; and is an investigator for Advanced Accelerator Applications, Amgen, AstraZeneca, Bayer, Constellation, Endocyte, Invitae, Janssen, Lantheus, Merck, POINT, Biopharma, Progenics, and Tenebio. Dr. Herrmann is a consultant to AAA, AstraZeneca, Bayer Healthcare, JNJ, Novartis, Curium, and Amgen; receives personal fees from Bayer, Sofie Biosciences, SIRTEX, Adacap, Curium, Endocyte, BTG, IPSEN, Siemens Healthineers, GE Healthcare, Amgen, Novartis, ymabs, Aktis Oncology, Theragnostics, Pharma15, Debiopharm, AstraZeneca, and Janssen; received a grant from BTG; received nonfinancial support from ABX; and received other support from Sofie Biosciences. The authors of this article have indicated no other relevant relationships that could be perceived as a real or apparent conflict of interest.CME Credit: SNMMI is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing education for physicians. SNMMI designates each JNM continuing education article for a maximum of 2.0 AMA PRA Category 1 Credits. Physicians should claim only credit commensurate with the extent of their participation in the activity. For CE credit, SAM, and other credit types, participants can access this activity through the SNMMI website (http://www.snmmilearningcenter.org) through June 2025.
  1. For correspondence or reprints, contact Oliver Sartor (osartor{at}tulane.edu).
View Full Text

Statistics from Altmetric.com

Cited By...

  • 8 Citations
  • 9 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Production Review of Accelerator-Based Medical Isotopes
    Yiwei Wang, Daiyuan Chen, Ricardo dos Santos Augusto, Jixin Liang, Zhi Qin, Juntao Liu, Zhiyi Liu
    Molecules 2022 27 16
  • [177Lu]Lu-PSMA-617 Versus Docetaxel in Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer: Final Survival Analysis of a Phase 2 Randomized, Controlled Trial
    Swayamjeet Satapathy, Bhagwant Rai Mittal, Ashwani Sood, Chandan Krushna Das, Ravimohan Suryanarayan Mavuduru, Shikha Goyal, Jaya Shukla, Shrawan Kumar Singh
    Journal of Nuclear Medicine 2023 64 11
  • Prostate-Specific Membrane Antigen-Targeted Therapy in Prostate Cancer: History, Combination Therapies, Trials, and Future Perspective
    Francesco Mattana, Lorenzo Muraglia, Antonio Barone, Marzia Colandrea, Yasmina Saker Diffalah, Silvia Provera, Alfio Severino Cascio, Emanuela Omodeo Salè, Francesco Ceci
    Cancers 2024 16 9
  • [177Lu]Lu-PSMA-617 theranostic probe for hepatocellular carcinoma imaging and therapy
    Qiaomiao Lu, Yu Long, Yongkang Gai, Qingyao Liu, Dawei Jiang, Xiaoli Lan
    European Journal of Nuclear Medicine and Molecular Imaging 2023 50 8
  • Clinical Trials of Prostate-Specific Membrane Antigen Radiopharmaceutical Therapy
    Hossein Jadvar, Patrick M. Colletti
    Journal of Nuclear Medicine Technology 2023 51 1
  • Synthesis and Preclinical Evaluation of Urea-Based Prostate-Specific Membrane Antigen-Targeted Conjugates Labeled with 177Lu
    Aleksei E. Machulkin, Stanislav A. Petrov, Vitalina Bodenko, Mariia S. Larkina, Evgenii Plotnikov, Feruza Yuldasheva, Maria Tretyakova, Ekaterina Bezverkhniaia, Nikolay Yu. Zyk, Elena Stasyuk, Roman Zelchan, Alexander G. Majouga, Vladimir Tolmachev, Anna Orlova, Elena K. Beloglazkina, Mekhman S. Yusubov
    ACS Pharmacology & Translational Science 2024 7 5
  • Construction of the Bioconjugate Py‐Macrodipa‐PSMA and Its In Vivo Investigations with Large 132/135La3+ and Small 47Sc3+ Radiometal Ions
    Aohan Hu, Kirsten E. Martin, Dariusz Śmiłowicz, Eduardo Aluicio‐Sarduy, Shelbie J. Cingoranelli, Suzanne E. Lapi, Jonathan W. Engle, Eszter Boros, Justin J. Wilson
    European Journal of Inorganic Chemistry 2023 26 35
  • Radiopharmaceutical Therapy
    Aohan Hu, Justin J. Wilson
    2023
  • Lu-177 PSMA vs Comparator Treatments and Survival in Metastatic Castration-Resistant Prostate Cancer
    Yu Yang Soon, Ian C. Marschner, Manjula Schou, Michael S. Hofman, Louise Emmett, Ian D. Davis, Martin R. Stockler, Andrew J. Martin
    JAMA Network Open 2024 7 9

Article usage

Article usage: July 2022 to May 2025

AbstractFullPdf
Jun 20228971367652
Jul 2022205587141
Aug 202212235481
Sep 202210238447
Oct 20226314662
Nov 20228429950
Dec 20226443641
Jan 20236750274
Feb 20235148554
Mar 20235950379
Apr 20235138344
May 20233936552
Jun 20232933140
Jul 20232229936
Aug 20232839433
Sep 20233136327
Oct 20232324031
Nov 20232722630
Dec 20232117342
Jan 20243130541
Feb 20242035633
Mar 20242319952
Apr 20242116150
May 20242417030
Jun 20242015939
Jul 20241720435
Aug 20242015140
Sep 20242714637
Oct 20243612044
Nov 2024129626
Dec 2024138132
Jan 20253410045
Feb 20251920238
Mar 20252513534
Apr 20253021541
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine: 63 (6)
Journal of Nuclear Medicine
Vol. 63, Issue 6
June 1, 2022
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Complete Issue (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Prostate Cancer Treatment: 177Lu-PSMA-617 Considerations, Concepts, and Limitations
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Prostate Cancer Treatment: 177Lu-PSMA-617 Considerations, Concepts, and Limitations
Oliver Sartor, Ken Herrmann
Journal of Nuclear Medicine Jun 2022, 63 (6) 823-829; DOI: 10.2967/jnumed.121.262413

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Prostate Cancer Treatment: 177Lu-PSMA-617 Considerations, Concepts, and Limitations
Oliver Sartor, Ken Herrmann
Journal of Nuclear Medicine Jun 2022, 63 (6) 823-829; DOI: 10.2967/jnumed.121.262413
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • THERANOSTICS
    • VISION STUDY DESIGN ENDPOINTS
    • VISION ELIGIBILITY CRITERIA
    • VISION STRATIFICATIONS, RANDOMIZATION, AND TREATMENTS
    • VISION STATISTICAL ANALYSIS PLAN
    • VISION PATIENT CHARACTERISTICS
    • VISION RESULTS
    • LIMITATIONS
    • FUTURE PHASE III TRIALS
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • [177Lu]Lu-PSMA-617 Versus Docetaxel in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer: Final Survival Analysis of a Phase 2 Randomized, Controlled Trial
  • Clinical Trials of Prostate-Specific Membrane Antigen Radiopharmaceutical Therapy
  • Google Scholar

More in this TOC Section

  • Approaches to Imaging Immune Activation Using PET
  • Large Language Models and Large Multimodal Models in Medical Imaging: A Primer for Physicians
  • Precision Oncology in Melanoma: Changing Practices
Show more Continuing Education

Similar Articles

Keywords

  • prostate cancer
  • castration-resistant
  • PSMA
  • theranostics
  • clinical trials
SNMMI

© 2025 SNMMI

Powered by HighWire