Exploiting the Full Potential of β-Amyloid and Tau PET Imaging for Drug Efficacy Testing

Example of so-called coffee break or dual–time-window imaging protocol, in this case for ¹⁸F-florbetaben amyloid PET scan (6). Gray-shadowed time windows represent significantly shortened (as compared with full dynamic imaging) scan times for patients, whereas data in in-between interval are interpolated. This protocol increases patient compliance while still providing full-quality quantitative data. It even allows for high patient throughput via interleaved patient scheduling on PET scanner.