Article Figures & Data
Figures
- FIGURE 1.
Example of amyloid PET/MR data with and without PVEC over time. Shown are baseline and 2-y follow-up MRI and gray matter (GM)–masked 18F-florbetapir PET data without and with PVEC for an Alzheimer dementia patient. Relative SUVR increase over time was higher with than without PVEC. GMD = gray matter density.
- FIGURE 2.
Effect of PVEC on correlation of MMSE and amyloid PET. Shown is regression analysis of baseline–to–follow-up composite SUVRs vs. baseline–to–follow-up MMSE scores for amyloid PET data with vs. without PVEC. Slope is significantly steeper for PVE-corrected data (F1 = 7.1, P = 0.008). Only data with baseline MMSE scores < 28 were included in this analysis.
Tables
Region Without PVEC With PVEC P Left frontal cortex 0.023 ± 0.14 0.067 ± 0.25 4.4 × 10−5 Right frontal cortex 0.022 ± 0.13 0.071 ± 0.23 1.6 × 10−6 Left temporal cortex 0.015 ± 0.11 0.058 ± 0.25 5.4 × 10−4 Right temporal cortex 0.017 ± 0.12 0.061 ± 0.27 7.5 × 10−4 Left parietal cortex 0.017 ± 0.15 0.070 ± 0.30 6.7 × 10−4 Right parietal cortex 0.021 ± 0.14 0.074 ± 0.32 1.7 × 10−3 Left hippocampus 0.007 ± 0.31 0.044 ± 0.50 0.027 Right hippocampus −0.007 ± 0.28 0.013 ± 0.35 0.17 Left Brodmann area 9 0.033 ± 0.17 0.085 ± 0.34 3.3 × 10−4 Right Brodmann area 9 0.030 ± 0.15 0.084 ± 0.30 1.8 × 10−5 Anterior cingulate 0.018 ± 0.14 0.063 ± 0.28 1.2 × 10−3 Occipital 0.009 ± 0.10 0.047 ± 0.27 0.023 Composite 0.017 ± 0.11 0.061 ± 0.22 1.9 × 10−4
Supplemental Data
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