Article Figures & Data
Figures
- FIGURE 1.
Mean absorbed dose coefficients for normal organs and tissues using ICRP 110 phantoms. Error bars = SD.
- FIGURE 2.
Absorbed dose coefficients for selected tissues from 16 patients using ICRP 110 phantoms.
- FIGURE 3.
Comparison of absorbed dose coefficients for ICRP 110 phantoms, CE phantoms (CEP), and previously published results by Walker et al. (9) using OLINDA/EXM, version 1. Error bars = SD. *Anatomic definition differs between ICRP 110 and CE phantoms. +ICRP 110 phantoms show alveolar–interstitial absorbed dose coefficient, compared with total lung for CE phantoms.
- FIGURE 4.
Contribution from target region, source region, and remainder of body to total absorbed dose coefficient in target regions ICRP 110 kidney (A), CE kidney (B), ICRP 110 urinary bladder wall (with contribution from contents and wall) (C), and CE urinary bladder wall (with contribution from contents) (D). CEP = CE phantoms.
Tables
Patient Age (y) Weight (kg) Height (cm) Sex Administered activity (MBq) PET/CT scans (n) 1F 59 63 155 F 156.9 3 2F 67 75 145 F 107.3 3 3F 70 74 147 F 140.6 4 4F 53 66 165 F 126.2 2 5F 35 76 161 F 107.3 3 6F 38 62 167 F 125.8 2 7F 65 109 159 F 82.1 3 8M 36 83 178 M 149.1 2 9F 79 73 156 F 177.6 3 10M 59 68 157 M 169.5 3 11M 63 102 182 M 158.7 3 12M 39 85 181 M 91.0 3 13F 43 97 155 F 112.1 2 14M 44 94 176 M 137.3 2 15F 52 106 162 F 126.5 3 16F 58 84 157 F 131.7 3 - TABLE 2
Absorbed Dose Coefficients for 68Ga-DOTATATE (mGy/MBq) in Normal Tissues and Organs
Site ICRP 110 CE Sandström et al. (10) Walker et al. (9) Spleen 0.25 ± 0.097 0.28 ± 0.11 0.11 ± 0.058 0.28 ± 0.12 Pituitary gland 0.15 ± 0.062 0.22 ± 0.092 — 0.042 ± 0.032 Kidneys 0.14 ± 0.048 0.15 ± 0.055 0.093 ± 0.016 0.092 ± 0.028 Adrenal glands 0.11 ± 0.037 0.11 ± 0.041 0.086 ± 0.052 0.015 ± 0.001 Liver 0.084 ± 0.019 0.088 ± 0.022 0.050 ± 0.015 0.045 ± 0.015 Gallbladder wall 0.043 ± 0.008 0.015 ± 0.002 0.016 ± 0.002 0.015 ± 0.001 Urinary bladder wall 0.040 ± 0.011 0.090 ± 0.033 0.098 ± 0.048 0.13 ± 0.062 Effective dose coefficient (mSv/MBq) 0.023 ± 0.003 0.027 ± 0.005 0.021 ± 0.003 0.026 ± 0.003 Male Female Site ICRP 110 CE ICRP 110 CE Whole body 1.48E+00 ± 5.67E−02 1.48E+00 ± 5.67E−02 1.48E+00 ± 9.77E−02 1.48E+00 ± 9.77E−02 Remainder of body 4.98E−01 ± 8.01E−02 6.49E−01 ± 6.28E−02 5.17E−01 ± 6.95E−02 6.01E−01 ± 7.63E−02 Muscle 3.17E−01 ± 8.14E−02 2.95E−01 ± 7.58E−02 2.11E−01 ± 7.34E−02 2.29E−01 ± 5.23E−02 Liver 2.90E−01 ± 4.89E−02 2.32E−01 ± 3.92E−02 3.18E−01 ± 5.48E−02 2.59E−01 ± 4.47E−02 Kidneys 8.56E−02 ± 7.97E−03 6.00E−02 ± 5.59E−03 1.25E−01 ± 3.35E−02 1.01E−01 ± 2.72E−02 Spleen 9.54E−02 ± 2.32E−02 7.59E−02 ± 1.84E−02 1.22E−01 ± 4.20E−02 1.03E−01 ± 3.55E−02 Lungs 6.78E−02 ± 1.39E−02 5.60E−02 ± 1.15E−02 5.98E−02 ± 1.97E−02 5.31E−02 ± 1.75E−02 Urinary bladder contents 6.07E−02 ± 1.92E−02 6.07E−02 ± 1.92E−02 5.76E−02 ± 2.16E−02 5.76E−02 ± 2.16E−02 Red marrow 4.47E−02 ± 2.41E−02 3.56E−02 ± 1.92E−02 4.59E−02 ± 2.36E−02 5.91E−02 ± 3.03E−02 Heart wall 8.59E−03 ± 1.54E−03 6.97E−03 ± 1.25E−03 7.48E−03 ± 1.83E−03 6.50E−03 ± 1.59E−03 Salivary glands 3.39E−03 ± 9.17E−04 — 4.87E−03 ± 1.91E−03 — Brain 4.26E−03 ± 5.30E−04 3.95E−03 ± 4.91E−04 6.10E−03 ± 1.36E−03 5.72E−03 ± 1.27E−03 Adrenal glands 2.91E−03 ± 3.55E−04 2.72E−03 ± 3.32E−04 3.88E−03 ± 1.41E−03 3.69E−03 ± 1.34E−03 Testes 7.60E−04 ± 1.07E−04 7.91E−04 ± 1.11E−04 — — Thyroid 6.86E−04 ± 3.10E−04 6.01E−04 ± 2.72E−04 4.64E−04 ± 1.68E−04 4.26E−04 ± 1.54E−04 Pituitary gland 2.71E−04 ± 6.96E−05 2.68E−04 ± 6.90E−05 4.49E−04 ± 1.49E−04 4.73E−04 ± 1.58E−04
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