18F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with 18F-FDG

Seock-Jin Chung; Hai-Jeon Yoon; Hyewon Youn; Mi Jeong Kim; Yun-Sang Lee; Jae Min Jeong; June-Key Chung; Keon Wook Kang; Lin Xie; Ming-Rong Zhang; Gi Jeong Cheon

doi:10.2967/jnumed.117.200667

Research ArticleMusculoskeletal

¹⁸F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with ¹⁸F-FDG

Seock-Jin Chung, Hai-Jeon Yoon, Hyewon Youn, Mi Jeong Kim, Yun-Sang Lee, Jae Min Jeong, June-Key Chung, Keon Wook Kang, Lin Xie, Ming-Rong Zhang and Gi Jeong Cheon

Journal of Nuclear Medicine May 2018, 59 (5) 839-845; DOI: https://doi.org/10.2967/jnumed.117.200667

Seock-Jin Chung

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

2Tumor Biology Program, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

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Hai-Jeon Yoon

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

4Department of Nuclear Medicine, College of Medicine, Ewha Womans University, Seoul, Korea

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Hyewon Youn

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

5Tumor Microenvironment Global Core Research Center, Seoul National University College of Medicine, Seoul, Korea

6Cancer Imaging Center, Seoul National University Hospital, Seoul, Korea

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Mi Jeong Kim

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

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Yun-Sang Lee

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

7Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea

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Jae Min Jeong

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

7Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea

8Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; and

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June-Key Chung

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

2Tumor Biology Program, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

5Tumor Microenvironment Global Core Research Center, Seoul National University College of Medicine, Seoul, Korea

7Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea

8Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; and

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Keon Wook Kang

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

2Tumor Biology Program, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

6Cancer Imaging Center, Seoul National University Hospital, Seoul, Korea

7Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea

8Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; and

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Lin Xie

9Department of Radiopharmaceutical Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan

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Ming-Rong Zhang

9Department of Radiopharmaceutical Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan

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Gi Jeong Cheon

1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

2Tumor Biology Program, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

7Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea

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May 1, 2018

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¹⁸F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with ¹⁸F-FDG

Seock-Jin Chung, Hai-Jeon Yoon, Hyewon Youn, Mi Jeong Kim, Yun-Sang Lee, Jae Min Jeong, June-Key Chung, Keon Wook Kang, Lin Xie, Ming-Rong Zhang, Gi Jeong Cheon

Journal of Nuclear Medicine May 2018, 59 (5) 839-845; DOI: 10.2967/jnumed.117.200667

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¹⁸F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with ¹⁸F-FDG

Seock-Jin Chung, Hai-Jeon Yoon, Hyewon Youn, Mi Jeong Kim, Yun-Sang Lee, Jae Min Jeong, June-Key Chung, Keon Wook Kang, Lin Xie, Ming-Rong Zhang, Gi Jeong Cheon

Journal of Nuclear Medicine May 2018, 59 (5) 839-845; DOI: 10.2967/jnumed.117.200667

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TSPO
Activated macrophage
rheumatoid arthritis
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¹⁸F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with ¹⁸F-FDG

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