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Research ArticleNeurology

Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET

Mony J. de Leon, Yi Li, Nobuyuki Okamura, Wai H. Tsui, Les A. Saint-Louis, Lidia Glodzik, Ricardo S. Osorio, Juan Fortea, Tracy Butler, Elizabeth Pirraglia, Silvia Fossati, Hee-Jin Kim, Roxana O. Carare, Maiken Nedergaard, Helene Benveniste and Henry Rusinek
Journal of Nuclear Medicine September 2017, 58 (9) 1471-1476; DOI: https://doi.org/10.2967/jnumed.116.187211
Mony J. de Leon
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
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Yi Li
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
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Nobuyuki Okamura
2Department of Pharmacology, Tohoku University School of Medicine, Tohoku, Japan
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Wai H. Tsui
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
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Les A. Saint-Louis
3Manhattan Diagnostic Radiology, New York, New York
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Lidia Glodzik
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
4Department of Radiology, New York University Center School of Medicine, New York, New York
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Ricardo S. Osorio
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
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Juan Fortea
5Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
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Tracy Butler
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
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Elizabeth Pirraglia
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
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Silvia Fossati
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
6Department of Neurology, New York University School of Medicine, New York, New York
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Hee-Jin Kim
1Department of Psychiatry, New York University School of Medicine, Center for Brain Health, New York, New York
7Department of Neurology, College of Medicine, Hanyang University, Seoul, Korea
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Roxana O. Carare
8Faculty of Medicine, University of Southampton, Southampton, United Kingdom
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Maiken Nedergaard
9Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, New York
10Center for Basic and Translational Neuroscience, University of Copenhagen, Copenhagen, Denmark; and
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Helene Benveniste
11Department of Anesthesiology, Yale School of Medicine, New Haven, Connecticut
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Henry Rusinek
4Department of Radiology, New York University Center School of Medicine, New York, New York
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Journal of Nuclear Medicine: 58 (9)
Journal of Nuclear Medicine
Vol. 58, Issue 9
September 1, 2017
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Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET
Mony J. de Leon, Yi Li, Nobuyuki Okamura, Wai H. Tsui, Les A. Saint-Louis, Lidia Glodzik, Ricardo S. Osorio, Juan Fortea, Tracy Butler, Elizabeth Pirraglia, Silvia Fossati, Hee-Jin Kim, Roxana O. Carare, Maiken Nedergaard, Helene Benveniste, Henry Rusinek
Journal of Nuclear Medicine Sep 2017, 58 (9) 1471-1476; DOI: 10.2967/jnumed.116.187211

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Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET
Mony J. de Leon, Yi Li, Nobuyuki Okamura, Wai H. Tsui, Les A. Saint-Louis, Lidia Glodzik, Ricardo S. Osorio, Juan Fortea, Tracy Butler, Elizabeth Pirraglia, Silvia Fossati, Hee-Jin Kim, Roxana O. Carare, Maiken Nedergaard, Helene Benveniste, Henry Rusinek
Journal of Nuclear Medicine Sep 2017, 58 (9) 1471-1476; DOI: 10.2967/jnumed.116.187211
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Keywords

  • Neurology
  • PET/CT
  • research methods
  • Alzheimer disease
  • CSF clearance
  • dynamic PET
  • THK5117
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