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Figures
- FIGURE 1.
Mechanisms enhancing efficacy of endoradiotherapy: cross-fire effect (CF, overlap of red circles) may compensate for target heterogeneity, RIBE (blue circle) leads to death of neighboring cells not directly exposed to irradiation, and abscopal effect (AbsE, green rectangle) induces responses also on remote lesions outside RIBE area and depends on induction of immune reactions.
- FIGURE 2.
Stratification of therapy according to bone marrow involvement. Maximum-intensity-projection PSMA ligand PET/CT in 2 patients. Patient lacking diffuse bone marrow infiltration (left) is candidate for treatment with 177Lu-PSMA ligand, whereas patient with infiltration of bone marrow (right) should be treated with 225Ac-PSMA ligand.
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