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Research ArticleRadiopharmaceuticals

Evaluation of Radiopharmaceutical Adverse Reaction Reports to the British Nuclear Medicine Society from 2007 to 2016

Tracia-Gay Kennedy-Dixon, Maxine Gossell-Williams, Margaret Cooper, Moez Trabelsi and Sobhan Vinjamuri
Journal of Nuclear Medicine December 2017, 58 (12) 2010-2012; DOI: https://doi.org/10.2967/jnumed.117.194092
Tracia-Gay Kennedy-Dixon
1Radiopharmacy, Royal Liverpool and Broadgreen University Hospitals Trust, Liverpool, United Kingdom
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Maxine Gossell-Williams
2Pharmacology Section, Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston, Jamaica; and
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Margaret Cooper
1Radiopharmacy, Royal Liverpool and Broadgreen University Hospitals Trust, Liverpool, United Kingdom
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Moez Trabelsi
1Radiopharmacy, Royal Liverpool and Broadgreen University Hospitals Trust, Liverpool, United Kingdom
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Sobhan Vinjamuri
3Royal Liverpool and Broadgreen University Hospitals Trust (consultant), Liverpool, United Kingdom
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    FIGURE 1.

    Number of reports of adverse reactions to radiopharmaceuticals each year from 2007 through 2016.

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    TABLE 1

    Previously Unreported Adverse Reactions and Probability of a Causal Relationship with the Radiopharmaceutical

    RadiopharmaceuticalAdverse reactionProbability
    111In-pentetreotideVaginal bleedingPossible
    18F-FDGNausea, vomiting, diarrhea, sweatingProbable
    51Cr-EDTADiscoloration of urineProbable
    68Ga-DOTANOCMaculopapular rashProbable
    99mTc-mercaptoacetyltriglycineVulvar inflammation and irritation; tremorsUnlikely
    99mTc-tetrofosminImpaired functionPossible
    75Se-tauroselcholic acidAnaphylaxis (rash, itching, flushing, swelling, dyspnea, throat constriction), nausea, indigestion, dizziness, burning sensation, painProbable
    TechnegasTinglingProbable
    • EDTA = ethylenediamine tetraacetic acid.

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Journal of Nuclear Medicine: 58 (12)
Journal of Nuclear Medicine
Vol. 58, Issue 12
December 1, 2017
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Evaluation of Radiopharmaceutical Adverse Reaction Reports to the British Nuclear Medicine Society from 2007 to 2016
Tracia-Gay Kennedy-Dixon, Maxine Gossell-Williams, Margaret Cooper, Moez Trabelsi, Sobhan Vinjamuri
Journal of Nuclear Medicine Dec 2017, 58 (12) 2010-2012; DOI: 10.2967/jnumed.117.194092

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Evaluation of Radiopharmaceutical Adverse Reaction Reports to the British Nuclear Medicine Society from 2007 to 2016
Tracia-Gay Kennedy-Dixon, Maxine Gossell-Williams, Margaret Cooper, Moez Trabelsi, Sobhan Vinjamuri
Journal of Nuclear Medicine Dec 2017, 58 (12) 2010-2012; DOI: 10.2967/jnumed.117.194092
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