Diagnostic value of SPECT/CT imaging for Brucellosis Spondylitis.

Objectives The aim of this study was to explore the imaging characteristics of SPECT/CT for spondylitis caused by brucells infections.

Methods 28 patients (14 males, 14 females, average age 46.4 years old, age range 25-71 years old) with Brucellosis Spondylitis confirmed by laboratory examination and pathology were involved. The images of whole body bone scan and SPECT/CT fusion imaging were retrospectively analyzed.

Results 76.7% Brucellosis spondylitis (43 of 56 lesions) were localized in lumbar, especially in L3, L4 and L5 vertebra(72.1%).Two or more consecutive vertebral involvements were seen in 20 of 28 patients (71.4%). Most lesions showed diffuse radioactive distribution at the body of affected vertebra, while 32.1% (18 of 56 lesions) only at the superior and inferior edge of the vertebra. 80.4% (45 of 56 lesions) were characterized with bone destruction in SPECT/CT imaging, which accompanied by hyperostosis and significant radioactivity concentration on the edge of the destruction area. Intervertebral discs were slightly involved. Vertebral abscess was rarely happened (5.4%). The diagnostic efficacy of brucellosis spondylitis using SPECT/CT was statistically significant higher than using SPECT (χ2=13.1, P<0.05).

Conclusions SPECT/CT fusion imaging can be used as an effective method for diagnosis of Brucellosis spondylitis.