Comparative Evaluation of the Biodistribution Profiles of a Series of Nonpeptidic Neurotensin Receptor-1 Antagonists Reveals a Promising Candidate for Theranostic Applications

Jörg Schulz; Martin Rohracker; Marvin Stiebler; Jürgen Goldschmidt; Oliver S. Grosser; Frank Osterkamp; Annette Pethe; Ulrich Reineke; Christiane Smerling; Holger Amthauer

doi:10.2967/jnumed.115.170530

Research ArticleBasic Science Investigations

Comparative Evaluation of the Biodistribution Profiles of a Series of Nonpeptidic Neurotensin Receptor-1 Antagonists Reveals a Promising Candidate for Theranostic Applications

Jörg Schulz, Martin Rohracker, Marvin Stiebler, Jürgen Goldschmidt, Oliver S. Grosser, Frank Osterkamp, Annette Pethe, Ulrich Reineke, Christiane Smerling and Holger Amthauer

Journal of Nuclear Medicine July 2016, 57 (7) 1120-1123; DOI: https://doi.org/10.2967/jnumed.115.170530

Jörg Schulz

1Klinik für Radiologie und Nuklearmedizin, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany

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Martin Rohracker

1Klinik für Radiologie und Nuklearmedizin, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany

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Marvin Stiebler

1Klinik für Radiologie und Nuklearmedizin, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany

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Jürgen Goldschmidt

2Leibniz-Institut für Neurobiologie, Magdeburg, Germany

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Oliver S. Grosser

1Klinik für Radiologie und Nuklearmedizin, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany

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Frank Osterkamp

33B Pharmaceuticals GmbH, Berlin, Germany; and

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Annette Pethe

1Klinik für Radiologie und Nuklearmedizin, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany

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Ulrich Reineke

33B Pharmaceuticals GmbH, Berlin, Germany; and

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Christiane Smerling

33B Pharmaceuticals GmbH, Berlin, Germany; and

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Holger Amthauer

1Klinik für Radiologie und Nuklearmedizin, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany

4Department of Nuclear Medicine, Charité–Universitätsmedizin, Berlin, Germany

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Journal of Nuclear Medicine

Vol. 57, Issue 7

July 1, 2016

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Comparative Evaluation of the Biodistribution Profiles of a Series of Nonpeptidic Neurotensin Receptor-1 Antagonists Reveals a Promising Candidate for Theranostic Applications

Jörg Schulz, Martin Rohracker, Marvin Stiebler, Jürgen Goldschmidt, Oliver S. Grosser, Frank Osterkamp, Annette Pethe, Ulrich Reineke, Christiane Smerling, Holger Amthauer

Journal of Nuclear Medicine Jul 2016, 57 (7) 1120-1123; DOI: 10.2967/jnumed.115.170530

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Comparative Evaluation of the Biodistribution Profiles of a Series of Nonpeptidic Neurotensin Receptor-1 Antagonists Reveals a Promising Candidate for Theranostic Applications

Jörg Schulz, Martin Rohracker, Marvin Stiebler, Jürgen Goldschmidt, Oliver S. Grosser, Frank Osterkamp, Annette Pethe, Ulrich Reineke, Christiane Smerling, Holger Amthauer

Journal of Nuclear Medicine Jul 2016, 57 (7) 1120-1123; DOI: 10.2967/jnumed.115.170530

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Keywords

NTR1-radiotracer
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SPECT/CT
biodistribution
oncology

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Comparative Evaluation of the Biodistribution Profiles of a Series of Nonpeptidic Neurotensin Receptor-1 Antagonists Reveals a Promising Candidate for Theranostic Applications

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