PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site–Inhibited Factor VII

Carsten H. Nielsen; Troels E. Jeppesen; Lotte K. Kristensen; Mette M. Jensen; Henrik H. El Ali; Jacob Madsen; Bo Wiinberg; Lars C. Petersen; Andreas Kjaer

doi:10.2967/jnumed.115.170266

Research ArticleBasic Science Investigations

PET Imaging of Tissue Factor in Pancreatic Cancer Using ⁶⁴Cu-Labeled Active Site–Inhibited Factor VII

Carsten H. Nielsen, Troels E. Jeppesen, Lotte K. Kristensen, Mette M. Jensen, Henrik H. El Ali, Jacob Madsen, Bo Wiinberg, Lars C. Petersen and Andreas Kjaer

Journal of Nuclear Medicine July 2016, 57 (7) 1112-1119; DOI: https://doi.org/10.2967/jnumed.115.170266

Carsten H. Nielsen

1Minerva Imaging, Copenhagen, Denmark

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Troels E. Jeppesen

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Lotte K. Kristensen

1Minerva Imaging, Copenhagen, Denmark

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Mette M. Jensen

1Minerva Imaging, Copenhagen, Denmark

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Henrik H. El Ali

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Jacob Madsen

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Bo Wiinberg

3Haemostasis Biology, Novo Nordisk A/S, Maalev, Denmark

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Lars C. Petersen

3Haemostasis Biology, Novo Nordisk A/S, Maalev, Denmark

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Andreas Kjaer

2Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; and

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Journal of Nuclear Medicine

Vol. 57, Issue 7

July 1, 2016

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PET Imaging of Tissue Factor in Pancreatic Cancer Using ⁶⁴Cu-Labeled Active Site–Inhibited Factor VII

Carsten H. Nielsen, Troels E. Jeppesen, Lotte K. Kristensen, Mette M. Jensen, Henrik H. El Ali, Jacob Madsen, Bo Wiinberg, Lars C. Petersen, Andreas Kjaer

Journal of Nuclear Medicine Jul 2016, 57 (7) 1112-1119; DOI: 10.2967/jnumed.115.170266

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PET Imaging of Tissue Factor in Pancreatic Cancer Using ⁶⁴Cu-Labeled Active Site–Inhibited Factor VII

Carsten H. Nielsen, Troels E. Jeppesen, Lotte K. Kristensen, Mette M. Jensen, Henrik H. El Ali, Jacob Madsen, Bo Wiinberg, Lars C. Petersen, Andreas Kjaer

Journal of Nuclear Medicine Jul 2016, 57 (7) 1112-1119; DOI: 10.2967/jnumed.115.170266

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Keywords

positron emission tomography (PET)
PET/CT
tissue factor (TF)
pancreatic cancer
64Cu
active site inhibited factor VII (FVIIai)
Molecular imaging
cancer
oncology

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