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Research ArticleClinical Investigations

Biodistribution and Radiation Dosimetry of the Anti-HER2 Affibody Molecule 68Ga-ABY-025 in Breast Cancer Patients

Mattias Sandström, Karolina Lindskog, Irina Velikyan, Anders Wennborg, Joachim Feldwisch, Dan Sandberg, Vladimir Tolmachev, Anna Orlova, Jens Sörensen, Jörgen Carlsson, Henrik Lindman and Mark Lubberink
Journal of Nuclear Medicine June 2016, 57 (6) 867-871; DOI: https://doi.org/10.2967/jnumed.115.169342
Mattias Sandström
1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Karolina Lindskog
1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Irina Velikyan
1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Anders Wennborg
2Affibody AB, Solna, Sweden
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Joachim Feldwisch
2Affibody AB, Solna, Sweden
3Biomedical Radiation Sciences, Rudbeck Laboratory, Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden; and
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Dan Sandberg
1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Vladimir Tolmachev
3Biomedical Radiation Sciences, Rudbeck Laboratory, Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden; and
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Anna Orlova
3Biomedical Radiation Sciences, Rudbeck Laboratory, Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden; and
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Jens Sörensen
1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Jörgen Carlsson
3Biomedical Radiation Sciences, Rudbeck Laboratory, Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden; and
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Henrik Lindman
4Section of Oncology, Department of Immunology, Genetics, and Pathology, Uppsala, Sweden
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Mark Lubberink
1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Article Information

vol. 57 no. 6 867-871
DOI 
https://doi.org/10.2967/jnumed.115.169342
PubMed 
26912439

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication November 9, 2015
  • Accepted for publication January 21, 2016
  • Published online June 1, 2016.

Article Versions

  • previous version (February 9, 2016 - 08:38).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Mattias Sandström1,
  2. Karolina Lindskog1,
  3. Irina Velikyan1,
  4. Anders Wennborg2,
  5. Joachim Feldwisch2,3,
  6. Dan Sandberg1,
  7. Vladimir Tolmachev3,
  8. Anna Orlova3,
  9. Jens Sörensen1,
  10. Jörgen Carlsson3,
  11. Henrik Lindman4 and
  12. Mark Lubberink1
  1. 1Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
  2. 2Affibody AB, Solna, Sweden
  3. 3Biomedical Radiation Sciences, Rudbeck Laboratory, Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden; and
  4. 4Section of Oncology, Department of Immunology, Genetics, and Pathology, Uppsala, Sweden
  1. For correspondence or reprints contact: Mattias Sandström, Medical Physics, Uppsala University Hospital, SE-75185, Uppsala, Sweden. E-mail: mattias.sandstrom{at}akademiska.se
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Journal of Nuclear Medicine: 57 (6)
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Biodistribution and Radiation Dosimetry of the Anti-HER2 Affibody Molecule 68Ga-ABY-025 in Breast Cancer Patients
Mattias Sandström, Karolina Lindskog, Irina Velikyan, Anders Wennborg, Joachim Feldwisch, Dan Sandberg, Vladimir Tolmachev, Anna Orlova, Jens Sörensen, Jörgen Carlsson, Henrik Lindman, Mark Lubberink
Journal of Nuclear Medicine Jun 2016, 57 (6) 867-871; DOI: 10.2967/jnumed.115.169342

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Biodistribution and Radiation Dosimetry of the Anti-HER2 Affibody Molecule 68Ga-ABY-025 in Breast Cancer Patients
Mattias Sandström, Karolina Lindskog, Irina Velikyan, Anders Wennborg, Joachim Feldwisch, Dan Sandberg, Vladimir Tolmachev, Anna Orlova, Jens Sörensen, Jörgen Carlsson, Henrik Lindman, Mark Lubberink
Journal of Nuclear Medicine Jun 2016, 57 (6) 867-871; DOI: 10.2967/jnumed.115.169342
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Keywords

  • affibody
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  • dosimetry
  • HER2-receptor
  • 68Ga-gallium
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