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Research ArticleClinical Investigations

Optimized Peptide Amount and Activity for ⁹⁰Y-Labeled DOTATATE Therapy

Peter Kletting, Thomas Kull, Christian Maaß, Noeen Malik, Markus Luster, Ambros J. Beer and Gerhard Glatting

Journal of Nuclear Medicine April 2016, 57 (4) 503-508; DOI: https://doi.org/10.2967/jnumed.115.164699

Peter Kletting

1Department of Nuclear Medicine, Ulm University, Ulm, Germany

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Thomas Kull

1Department of Nuclear Medicine, Ulm University, Ulm, Germany

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Christian Maaß

2Medical Radiation Physics/Radiation Protection, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; and

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Noeen Malik

1Department of Nuclear Medicine, Ulm University, Ulm, Germany

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Markus Luster

3Klinik für Nuklearmedizin, Universität Marburg, Marburg, Germany

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Ambros J. Beer

1Department of Nuclear Medicine, Ulm University, Ulm, Germany

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Gerhard Glatting

2Medical Radiation Physics/Radiation Protection, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; and

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Journal of Nuclear Medicine: 57 (4)

Journal of Nuclear Medicine

Vol. 57, Issue 4

April 1, 2016

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Optimized Peptide Amount and Activity for ⁹⁰Y-Labeled DOTATATE Therapy

Peter Kletting, Thomas Kull, Christian Maaß, Noeen Malik, Markus Luster, Ambros J. Beer, Gerhard Glatting

Journal of Nuclear Medicine Apr 2016, 57 (4) 503-508; DOI: 10.2967/jnumed.115.164699

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Optimized Peptide Amount and Activity for ⁹⁰Y-Labeled DOTATATE Therapy

Peter Kletting, Thomas Kull, Christian Maaß, Noeen Malik, Markus Luster, Ambros J. Beer, Gerhard Glatting

Journal of Nuclear Medicine Apr 2016, 57 (4) 503-508; DOI: 10.2967/jnumed.115.164699

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Keywords

PBPK modeling
PRRT
90Y-DOTATATE
peptide amount
biologically effective dose (BED)

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