Complementary, Selective PET Imaging of Integrin Subtypes α5β1 and αvβ3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin

Johannes Notni; Katja Steiger; Frauke Hoffmann; Dominik Reich; Tobias G. Kapp; Florian Rechenmacher; Stefanie Neubauer; Horst Kessler; Hans-Jürgen Wester

doi:10.2967/jnumed.115.165720

Research ArticleBasic Science Investigations

Complementary, Selective PET Imaging of Integrin Subtypes α₅β₁ and α_vβ₃ Using ⁶⁸Ga-Aquibeprin and ⁶⁸Ga-Avebetrin

Johannes Notni, Katja Steiger, Frauke Hoffmann, Dominik Reich, Tobias G. Kapp, Florian Rechenmacher, Stefanie Neubauer, Horst Kessler and Hans-Jürgen Wester

Journal of Nuclear Medicine March 2016, 57 (3) 460-466; DOI: https://doi.org/10.2967/jnumed.115.165720

Johannes Notni

1Lehrstuhl für Pharmazeutische Radiochemie, Technische Universität München, Garching, Germany

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Katja Steiger

2Institute of Pathology, Technische Universität München, Munich, Germany; and

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Frauke Hoffmann

1Lehrstuhl für Pharmazeutische Radiochemie, Technische Universität München, Garching, Germany

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Dominik Reich

1Lehrstuhl für Pharmazeutische Radiochemie, Technische Universität München, Garching, Germany

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Tobias G. Kapp

3Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Munich, Germany

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Florian Rechenmacher

3Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Munich, Germany

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Stefanie Neubauer

3Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Munich, Germany

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Horst Kessler

3Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Munich, Germany

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Hans-Jürgen Wester

1Lehrstuhl für Pharmazeutische Radiochemie, Technische Universität München, Garching, Germany

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Journal of Nuclear Medicine

Vol. 57, Issue 3

March 1, 2016

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Complementary, Selective PET Imaging of Integrin Subtypes α₅β₁ and α_vβ₃ Using ⁶⁸Ga-Aquibeprin and ⁶⁸Ga-Avebetrin

Johannes Notni, Katja Steiger, Frauke Hoffmann, Dominik Reich, Tobias G. Kapp, Florian Rechenmacher, Stefanie Neubauer, Horst Kessler, Hans-Jürgen Wester

Journal of Nuclear Medicine Mar 2016, 57 (3) 460-466; DOI: 10.2967/jnumed.115.165720

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Complementary, Selective PET Imaging of Integrin Subtypes α₅β₁ and α_vβ₃ Using ⁶⁸Ga-Aquibeprin and ⁶⁸Ga-Avebetrin

Johannes Notni, Katja Steiger, Frauke Hoffmann, Dominik Reich, Tobias G. Kapp, Florian Rechenmacher, Stefanie Neubauer, Horst Kessler, Hans-Jürgen Wester

Journal of Nuclear Medicine Mar 2016, 57 (3) 460-466; DOI: 10.2967/jnumed.115.165720

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Keywords

angiogenesis
Positron Emission Tomography
68Ga
integrins
immunohistochemistry

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