Article Figures & Data
Figures
- FIGURE 1.
In-house–made mouse phantom with thin silicone tube drawn through the channels and point source placed on top.
- FIGURE 2.
True coincidence counting rates detected on Genisys4, Inveon, and NanoPET/CT when high activities of 18F were allowed to decay in PET system in Study 1. (On NanoPET/CT, available counting rates were plotted.)
- FIGURE 3.
Coincidence counting rates when 22Na point source was imaged together with decaying 99mTc (Study 2A) for Genisys4 (A), Inveon (B), and NanoPET/CT (C). B also presents corrected counting rate for Study 2A for Inveon. C also presents coincidence counting rates for decaying 99mTc (Study 2B) and 22Na point source imaged together with decaying 177Lu (Study 2C) on NanoPET/CT.
- FIGURE 4.
Volume resolution for Genisys4 (A), Inveon (B), and NanoPET/CT (C) measured over 22Na point source imaged together with decaying 99mTc (Study 2A). C also presents volume resolution measured over 22Na point source together with decaying 177Lu for NanoPET/CT (Study 2C). FWHM = full width at half maximum; FWTM = full width at tenth maximum.
- FIGURE 5.
Comparison of true coincidence counting rates detected for 18F decaying alone (Study 1) or together with 99mTc (Study 3) on Genisys4 (A), Inveon (B), and NanoPET/CT (C). (On NanoPET/CT, available counting rates were plotted.) B also presents corrected counting rate for Study 3 for Inveon.
Tables
Characteristic Inveon NanoPET/CT Genisys4 Detector material LSO LYSO:Ce BGO Crystal dimensions (mm3) 1.5 × 1.5 × 10 1.12 × 1.12 × 13 1.8 × 1.8 × 7 Axial field of view (mm) 127 95 94 Transaxial field of view (mm) 100 123 45 Energy window (keV) 350–650 400–600 150–650 Coincidence window (ns) 3.4 5 20 Sensitivity (%) 6.7 7.7 14 Image spatial resolution (mm) 1.8 1 1.4 Energy resolution (511 keV) (%) 14.6 19 18.0 Crystal decay time (ns) 47 41 300 Number of detectors 64 12 4 Number of crystals per detector 400 1,200 3,159 BGO = bismuth germanate; LSO = lutetium oxyorthosilicate; LYSO = lutetium yttrium orthosilicate.
Activity (MBq) Study Phantom Inveon Genisys4 NanoPET/CT 1 Sphere*/NEMA 270 (18F) 11 (18F) 250 (18F) 2A Point source and block† 500 (99mTc), 0.074 (22Na) 170 (99mTc), 0.074 (22Na) 550 (99mTc), 0.43 (22Na) 2B Sphere — — 480 (99mTc) 2C Point source and block† — — 82 (177Lu), 0.43 (22Na) 3 Sphere‡/NEMA 7.7 (18F), 110 (99mTc) 0.85 (18F), 0.71 (99mTc) 12 (18F), 64 (99mTc) Isotope Half-life Decay mode Q-value (keV) Branching (%) γ-emission (keV) γ-yield (%) 177Lu 6.734 d β− 498.3 100 113 6.4 208 11.0 18F 109.77 m e, β+ 1,655.5 3.27 — — 633.5 96.73 99mTc 6.01 h IT — 100 140.511 89 142.628 0.0187 22Na 2.6019 y e, β+ 2,842.2 100 1,274.53 99.944 e = electron capture; IT = isomeric transition.
