The Imaging and Radiation Oncology Core (IROC) Effort for the NCI National Clinical Trial Network (NCTN)

Learning Objectives To provide an overview of the NCI National Clinical Trial Network To introduce the IROC cooperative to the Nuclear Medicine and Molecular Imaging community To educate about current NCTN trials that utilize Nuclear Medicine and Molecular Imaging agents To present relevant qualification and credentialing aspects of Nuclear Medicine procedures To review current service standard for NCTN clinical trials To present current quality assurance performance characterisics in NCTN trial using Nuclear Imaging methodologies

This exhibit introduces the organization and forward looking vision of the NCI NCTN U24 IROC effort organized with the American College of Radiology to provide a fully integrated, comprehensive quality assurance effort for Imaging and Radiation Oncology for the five network groups of the NCI National Clinical Trial Network. This effort integrates six QA centers: the ACRIN Core Laboratory (Philadelphia), the Alliance and SWOG Imaging Core Lab at OSU, the QARC (Rhode Island), the RPC at MD Anderson, the ATC (Wash U in St. Louis) and RTOG Core Lab (Philadelphia). Unified qualification, credentialing and quality assurance procedures will cover all aspects of this service that brings an unmatched ability to manage standarization and quality for imaging and radiation oncology within oncologic trials. This exhibit will detail the special aspects relevant for Nuclear Medicine imaging procedures within NCTN clinical trials as well as recent and current active trials that use nuclear medicine/molecular imaging procedures as important response assessment markers. Another focus of this exhibit is the overview on the established service standards applicable to Nuclear Medicine procedures.

Research Support This research effort is supported by the NIH 1U24CA180803