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Research ArticleClinical Investigations

Methods of CT Dose Estimation in Whole-Body 18F-FDG PET/CT

Yusuke Inoue, Kazunori Nagahara, Yoshihito Tanaka, Hiroki Miyatake, Hirofumi Hata and Toshimasa Hara
Journal of Nuclear Medicine May 2015, 56 (5) 695-700; DOI: https://doi.org/10.2967/jnumed.114.153718
Yusuke Inoue
1Department of Diagnostic Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; and
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Kazunori Nagahara
2Department of Radiology, Kitasato University Hospital, Sagamihara, Japan
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Yoshihito Tanaka
2Department of Radiology, Kitasato University Hospital, Sagamihara, Japan
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Hiroki Miyatake
2Department of Radiology, Kitasato University Hospital, Sagamihara, Japan
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Hirofumi Hata
2Department of Radiology, Kitasato University Hospital, Sagamihara, Japan
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Toshimasa Hara
1Department of Diagnostic Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; and
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  • FIGURE 1.
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    FIGURE 1.

    Division of scan range into 6 anatomic regions (head, neck, chest, abdomen, pelvis, and proximal thigh) is shown on display of CT-Expo software for male subject.

  • FIGURE 2.
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    FIGURE 2.

    Regional ED values in group A estimated by CT-Expo method (white bars), regional DLP method (black bars), and simple DLP method (shaded bars). Means and SDs in men (A), women (B), and all patients (C) are presented.

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    FIGURE 3.

    Relationships of EDs estimated by different methods in group A. Estimates of regional DLP method (A) and simple DLP method (B) are plotted against those of CT-Expo method. Line of identity is also shown. ○ = data for men; △ = data for women.

  • FIGURE 4.
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    FIGURE 4.

    Relationships of ED/DLP with body height (A) and body weight (B). Linear regression lines, regression equations, and Spearman correlation coefficients are shown. ○ = data for men; △ = data for women.

Tables

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    TABLE 1

    Patient Characteristics

    Group AGroup B
    CharacteristicMaleFemaleAllMaleFemaleAll
    Age (y)65.2 ± 13.161.9 ± 15.963.6 ± 14.568.5 ± 9.064.5 ± 11.966.5 ± 10.6
    Body height (cm)166.8 ± 6.1154.1 ± 6.8160.4 ± 9.1164.4 ± 4.9152.9 ± 7.3158.7 ± 8.4
    Body weight (kg)64.6 ± 12.849.1 ± 8.856.8 ± 13.465.8 ± 15.855.6 ± 18.360.7 ± 17.7
    • Values are mean ± SD.

    • View popup
    TABLE 2

    Whole-Body ED Values in Group A

    ED (mSv)
    MethodMaleFemaleAll
    CT-Expo4.49 ± 0.814.40 ± 0.724.44 ± 0.76
    Regional DLP5.01 ± 1.043.98 ± 0.814.49 ± 1.06
    Simple DLP5.78 ± 1.124.69 ± 0.875.23 ± 1.14
    • Data are mean ± SD.

    • View popup
    TABLE 3

    ED/DLP (mSv/mGy/cm)

    SubjectMaleFemaleAll
    Group A0.0117 ± 0.00050.0142 ± 0.00100.0129 ± 0.0015
    Group A + B0.0117 ± 0.00050.0141 ± 0.00090.0129 ± 0.0015
    • Data are mean ± SD. Group A + B represents subjects pooled from groups A and B.

    • View popup
    TABLE 4

    Whole-Body ED Values in Group B

    ED (mSv)
    MethodConversion factorMaleFemaleAll
    CT-Expo4.69 ± 1.105.01 ± 1.474.85 ± 1.29
    Simple DLPOriginal5.93 ± 1.395.26 ± 1.685.60 ± 1.56
    Simple DLPModified5.14 ± 1.214.56 ± 1.464.85 ± 1.35
    Simple DLPSex-specific4.74 ± 1.114.91 ± 1.574.83 ± 1.35
    • Data are mean ± SD.

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Journal of Nuclear Medicine: 56 (5)
Journal of Nuclear Medicine
Vol. 56, Issue 5
May 1, 2015
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Methods of CT Dose Estimation in Whole-Body 18F-FDG PET/CT
Yusuke Inoue, Kazunori Nagahara, Yoshihito Tanaka, Hiroki Miyatake, Hirofumi Hata, Toshimasa Hara
Journal of Nuclear Medicine May 2015, 56 (5) 695-700; DOI: 10.2967/jnumed.114.153718

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Methods of CT Dose Estimation in Whole-Body 18F-FDG PET/CT
Yusuke Inoue, Kazunori Nagahara, Yoshihito Tanaka, Hiroki Miyatake, Hirofumi Hata, Toshimasa Hara
Journal of Nuclear Medicine May 2015, 56 (5) 695-700; DOI: 10.2967/jnumed.114.153718
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