A Tyrosine Kinase Inhibitor–Based High-Affinity PET Radiopharmaceutical Targets Vascular Endothelial Growth Factor Receptor

Feng Li; Sheng Jiang; Youli Zu; Daniel Y. Lee; Zheng Li

doi:10.2967/jnumed.114.138925

Research ArticleBasic Science Investigations

A Tyrosine Kinase Inhibitor–Based High-Affinity PET Radiopharmaceutical Targets Vascular Endothelial Growth Factor Receptor

Feng Li, Sheng Jiang, Youli Zu, Daniel Y. Lee and Zheng Li

Journal of Nuclear Medicine September 2014, 55 (9) 1525-1531; DOI: https://doi.org/10.2967/jnumed.114.138925

Feng Li

1Department of Translational Imaging, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas

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Sheng Jiang

2Laboratory of Medicinal Chemistry, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China; and

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Youli Zu

3Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas

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Daniel Y. Lee

1Department of Translational Imaging, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas

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Zheng Li

1Department of Translational Imaging, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas

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vol. 55 no. 9 1525-1531

DOI

https://doi.org/10.2967/jnumed.114.138925

PubMed

24970912

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Society of Nuclear Medicine

Print ISSN

0161-5505

Online ISSN

2159-662X

History

Received for publication February 11, 2014
Accepted for publication May 6, 2014
Published online September 2, 2014.

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Author Information

Feng Li¹,
Sheng Jiang²,
Youli Zu³,
Daniel Y. Lee¹ and
Zheng Li¹

¹Department of Translational Imaging, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas
²Laboratory of Medicinal Chemistry, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China; and
³Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas

For correspondence or reprints contact: Zheng Li, Houston Methodist Research Institute, 6670 Bertner St., Houston, TX 77030. E-mail: zli{at}houstonmethodist.org

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A Tyrosine Kinase Inhibitor–Based High-Affinity PET Radiopharmaceutical Targets Vascular Endothelial Growth Factor Receptor

Feng Li, Sheng Jiang, Youli Zu, Daniel Y. Lee, Zheng Li

Journal of Nuclear Medicine Sep 2014, 55 (9) 1525-1531; DOI: 10.2967/jnumed.114.138925

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A Tyrosine Kinase Inhibitor–Based High-Affinity PET Radiopharmaceutical Targets Vascular Endothelial Growth Factor Receptor

Feng Li, Sheng Jiang, Youli Zu, Daniel Y. Lee, Zheng Li

Journal of Nuclear Medicine Sep 2014, 55 (9) 1525-1531; DOI: 10.2967/jnumed.114.138925

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Keywords

vascular endothelial growth factor receptor (VEGFR)
tumor angiogenesis
64Cu
theranostic

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