Article Figures & Data
Figures
- FIGURE 1.
A 54-y-old man presented with papillary thyroid cancer metastatic to lungs and lymph nodes. (A) After surgery, dosimetrically derived therapy was done, and anterior posttherapy scan is shown. Multiple subsequent treatments were given for residual disease. (B) Representative anterior posttherapy scan showing residual disease in lungs. (C) Anterior image from final diagnostic scan showing no remaining visible disease. In total, this patient received more than 74 GBq across multiple dosimetric treatments and achieved years of progression-free survival while maintaining acceptable hematologic and lung function.
- FIGURE 2.
Various signaling pathways in cancers that are amenable to targeted therapies. Sorafenib has inhibitory effects on multiple pathways. EGFR = endothelial growth factor receptor; HIF-1 = hypoxia-inducible factor-1; HIF-2 = hypoxia-inducible factor-2; PDGF = platelet-derived growth factor; SF = sorafenib; TFGα = tumor growth factor α; VEGF = vascular endothelial growth factor; VHL = von Hippel Lindau. (Reprinted with permission of (54).)
